Gut microbiome, big data and machine learning to promote precision medicine for cancer
The gut microbiome has been implicated in cancer in several ways, as specific microbial
signatures are known to promote cancer development and influence safety, tolerability and …
signatures are known to promote cancer development and influence safety, tolerability and …
Machine learning techniques for personalised medicine approaches in immune-mediated chronic inflammatory diseases: applications and challenges
In the past decade, the emergence of machine learning (ML) applications has led to
significant advances towards implementation of personalised medicine approaches for …
significant advances towards implementation of personalised medicine approaches for …
Environmental factors shaping the gut microbiome in a Dutch population
The gut microbiome is associated with diverse diseases,–, but a universal signature of a
healthy or unhealthy microbiome has not been identified, and there is a need to understand …
healthy or unhealthy microbiome has not been identified, and there is a need to understand …
Long-term dietary patterns are associated with pro-inflammatory and anti-inflammatory features of the gut microbiome
Objective The microbiome directly affects the balance of pro-inflammatory and anti-
inflammatory responses in the gut. As microbes thrive on dietary substrates, the question …
inflammatory responses in the gut. As microbes thrive on dietary substrates, the question …
Impact of commonly used drugs on the composition and metabolic function of the gut microbiota
The human gut microbiota has now been associated with drug responses and efficacy, while
chemical compounds present in these drugs can also impact the gut bacteria. However …
chemical compounds present in these drugs can also impact the gut bacteria. However …
[HTML][HTML] Host genetic regulation of human gut microbial structural variation
Although the impact of host genetics on gut microbial diversity and the abundance of specific
taxa is well established,,,,–, little is known about how host genetics regulates the genetic …
taxa is well established,,,,–, little is known about how host genetics regulates the genetic …
Gut microbial co-abundance networks show specificity in inflammatory bowel disease and obesity
L Chen, V Collij, M Jaeger… - Nature …, 2020 - nature.com
The gut microbiome is an ecosystem that involves complex interactions. Currently, our
knowledge about the role of the gut microbiome in health and disease relies mainly on …
knowledge about the role of the gut microbiome in health and disease relies mainly on …
Location-specific signatures of Crohn's disease at a multi-omics scale
Background Crohn's disease (CD), an inflammatory bowel disease (IBD) subtype, results
from pathologic interactions between host cells and its resident gut microbes. CD manifests …
from pathologic interactions between host cells and its resident gut microbes. CD manifests …
Role of probiotics in the management of COVID-19: A computational perspective
Coronavirus disease 2019 (COVID-19) was declared a pandemic at the beginning of 2020,
causing millions of deaths worldwide. Millions of vaccine doses have been administered …
causing millions of deaths worldwide. Millions of vaccine doses have been administered …
16S rRNA and metagenomic shotgun sequencing data revealed consistent patterns of gut microbiome signature in pediatric ulcerative colitis
Dysbiosis of human gut microbiota has been reported in association with ulcerative colitis
(UC) in both children and adults using either 16S rRNA gene or shotgun sequencing data …
(UC) in both children and adults using either 16S rRNA gene or shotgun sequencing data …