Molecular mimicry and autoimmunity in the time of COVID-19

M Rojas, M Herrán, C Ramírez-Santana… - Journal of …, 2023 - Elsevier
Infectious diseases are commonly implicated as potential initiators of autoimmune diseases
(ADs) and represent the most commonly known factor in the development of autoimmunity in …

Unravelling antigenic cross-reactions toward the world of coronaviruses: extent of the stability of shared epitopes and SARS-CoV-2 anti-spike cross-neutralizing …

CA Devaux, J Fantini - Pathogens, 2023 - mdpi.com
The human immune repertoire retains the molecular memory of a very great diversity of
target antigens (epitopes) and can recall this upon a second encounter with epitopes …

Ethno‐demographic disparities in humoral responses to the COVID‐19 vaccine among healthcare workers

P Ahluwalia, A Vashisht, H Singh… - Journal of Medical …, 2023 - Wiley Online Library
The COVID‐19 pandemic had a profound impact on global health, but rapid vaccine
administration resulted in a significant decline in morbidity and mortality rates worldwide. In …

Faradaic Impedimetric Immunosensor for Label-Free Point-of-Care Detection of COVID-19 Antibodies Using Gold-Interdigitated Electrode Array

LCT Shoute, CL Charlton, JN Kanji, S Babiuk, L Babiuk… - Biosensors, 2023 - mdpi.com
Label-free electrochemical biosensors have many desirable characteristics in terms of
miniaturization, scalability, digitization, and other attributes associated with point-of-care …

Low-dose M.tb infection but not BCG or MTBVAC vaccination enhances heterologous antibody titres in non-human primates

MP Peralta Alvarez, H Jones… - Frontiers in …, 2024 - frontiersin.org
Introduction Mycobacteria are known to exert a range of heterologous effects on the immune
system. The mycobacteria-based Freund's Complete Adjuvant is a potent non-specific …

High frequencies of alpha common cold coronavirus/SARS-CoV-2 cross-reactive functional CD4+ and CD8+ memory T cells are associated with protection from …

PG Coulon, S Prakash, NR Dhanushkodi… - Frontiers in …, 2024 - frontiersin.org
Background Cross-reactive SARS-CoV-2-specific memory CD4+ and CD8+ T cells are
present in up to 50% of unexposed, pre-pandemic, healthy individuals (UPPHIs). However …

Comparison of Six Aptamer-Aptamer Pairs on Rapid Detection of SARS-CoV-2 by Lateral Flow Assay

D Çam Derin, E Gültekin, E Gündüz… - Journal of AOAC …, 2024 - academic.oup.com
Background SARS-CoV-2 is a threat to humanity. Both the spike (S) protein and its receptor
binding domain (sRBD) are extensively used for rapid detection. Although real-time reverse …

Bioinformatical design and performance evaluation of a nucleocapsid-and an RBD-based particle enhanced turbidimetric immunoassay (PETIA) to quantify the wild …

L Wey, T Masetto, A Spaeth, J Brehm, C Kochem… - Biomedicines, 2023 - mdpi.com
Since SARS-CoV-2 emerged in December 2019 in Wuhan, the resulting pandemic has
paralyzed the economic and cultural life of the world. Variants of concern (VOC) strongly …

Unveiling the intricacies of COVID‐19: Autoimmunity, multi‐organ manifestations and the role of autoantibodies

Z Ding, X Wei, H Pan, H Shi… - Scandinavian Journal of …, 2024 - Wiley Online Library
COVID‐19 is a severe infectious disease caused by a SARS‐CoV‐2 infection. It has caused
a global pandemic and can lead to acute respiratory distress syndrome (ARDS). Beyond the …

High-throughput screening identifies broad-spectrum Coronavirus entry inhibitors

S Khan, EO Partuk, J Chiaravalli, N Kozer, KA Shurrush… - iScience, 2024 - cell.com
The COVID-19 pandemic highlighted the need for antivirals against emerging coronaviruses
(CoV). Inhibiting spike (S) glycoprotein-mediated viral entry is a promising strategy. To …