Loss of calcium in human spermatozoa via EPPIN, the semenogelin receptor

MG O'Rand, EE Widgren - Biology of reproduction, 2012 - academic.oup.com
The development of a new male contraceptive requires a transition from animal model to
human and an understanding of the mechanisms involved in the target's inhibition of human …

Na+/Ca2+ exchanger modulates the flagellar wave pattern for the regulation of motility activation and chemotaxis in the ascidian spermatozoa

K Shiba, T Márián, Z Krasznai, SA Baba… - Cell motility and the …, 2006 - Wiley Online Library
Ion channels and ion exchangers are known to be important participants in various aspects
of sperm physiology, eg motility activation, chemotaxis, the maintenance of motility and the …

The role of bicarbonate in the modulation of capacitation, spontaneous acrosome reaction and motility of equine fresh and frozen spermatozoa

M Albrizio, GM Lacalandra, M Cinone - Theriogenology, 2022 - Elsevier
In this study, we defined the composition of the culture medium that yield a significant
percentage of alive and functional equine spermatozoa during enough time before artificial …

[PDF][PDF] Hexane fraction of Prunus japonica thunb. Seed extract enhances boar sperm motility via CatSper ion channel

A Cooray, MR Chae, TD Wijerathne, DG Kim, J Kim… - Heliyon, 2023 - cell.com
Introduction Mammalian sperm motility is facilitated by flagellar beating, which depends on
active ion movement through ion channels and their regulation. Prunus japonica Thunb …

[HTML][HTML] Signaling Roleplay between Ion Channels during Mammalian Sperm Capacitation

F Benko, D Urminská, M Ďuračka, E Tvrdá - Biomedicines, 2023 - mdpi.com
In order to accomplish their primary goal, mammalian spermatozoa must undergo a series of
physiological, biochemical, and functional changes crucial for the acquisition of fertilization …

Functional implications of membrane modification with semenogelins for inhibition of sperm motility in humans

K Yoshida, ZT Krasznai, Z Krasznai… - Cell Motility and the …, 2009 - Wiley Online Library
Abstract Semenogelin I and II (Sgs) are the major component of human semen coagulum.
The protein is rapidly cleaved after ejaculation by a prostate‐specific antigen, resulting in …

[HTML][HTML] The use of anti-VDAC2 antibody for the combined assessment of human sperm acrosome integrity and ionophore A23187-induced acrosome reaction

B Liu, P Wang, Z Wang, W Zhang - PLoS One, 2011 - journals.plos.org
Voltage-dependent anion channel (VDAC) is mainly located in the mitochondrial outer
membrane and participates in many biological processes. In mammals, three VDAC …

[PDF][PDF] Potential role of Catsper and proton ion channels in bull fertility

J Gogoi, M Mondal, P Pal, VR Upadhyay… - J. Pharm …, 2022 - thepharmajournal.com
Sperm ion channels play a key role in animal fertility. For successful fertilization, sperm
motility, chemotaxis, capacitation and the acrosome reaction are few of the important …

Regulation of hamster sperm hyperactivation by extracellular Na

GL Takei, M Fujinoki - Reproduction, 2016 - rep.bioscientifica.com
Mammalian sperm motility has to be hyperactivated to be fertilization-competent.
Hyperactivation is regulated by extracellular environment. Osmolality of mammalian semen …

Intracellular sodium increase induced by external calcium removal in human sperm

V Torres‐Flores, NL García‐Sánchez… - Journal of …, 2008 - Wiley Online Library
In human sperm, removal of external calcium produces a fast Na+‐dependent
depolarization that is presumably due to sodium permeation through calcium channels …