[HTML][HTML] 'Spikeopathy': COVID-19 spike protein is pathogenic, from both virus and vaccine mRNA

PI Parry, A Lefringhausen, C Turni, CJ Neil, R Cosford… - Biomedicines, 2023 - mdpi.com
The COVID-19 pandemic caused much illness, many deaths, and profound disruption to
society. The production of 'safe and effective'vaccines was a key public health target. Sadly …

[HTML][HTML] NLRP3 inflammasome activation and SARS-CoV-2-mediated hyperinflammation, cytokine storm and neurological syndromes

D Dutta, J Liu, H Xiong - International journal of physiology …, 2022 - ncbi.nlm.nih.gov
Despite the introduction of vaccines and drugs for SARS-CoV-2, the COVID-19 pandemic
continues to spread throughout the world. In severe COVID-19 patients, elevated levels of …

[HTML][HTML] Innate immune suppression by SARS-CoV-2 mRNA vaccinations: The role of G-quadruplexes, exosomes, and MicroRNAs

S Seneff, G Nigh, AM Kyriakopoulos… - Food and Chemical …, 2022 - Elsevier
Abstract The mRNA SARS-CoV-2 vaccines were brought to market in response to the public
health crises of Covid-19. The utilization of mRNA vaccines in the context of infectious …

[HTML][HTML] SARS-CoV-2 Spike protein alters microglial purinergic signaling

VS Alves, SACS Santos, R Leite-Aguiar… - Frontiers in …, 2023 - frontiersin.org
Despite long-term sequelae of COVID-19 are emerging as a substantial public health
concern, the mechanism underlying these processes still unclear. Evidence demonstrates …

[HTML][HTML] Circulating microRNAs as emerging regulators of COVID-19

Y Liang, D Fang, X Gao, X Deng, N Chen, J Wu… - Theranostics, 2023 - ncbi.nlm.nih.gov
Abstract Coronavirus disease 2019 (COVID-19), an infectious disease caused by the novel
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global pandemic that …

Altered increase in STAT1 expression and phosphorylation in severe COVID‐19

H Rincon‐Arevalo, A Aue, J Ritter… - European journal of …, 2022 - Wiley Online Library
The interferon pathway, a key antiviral defense mechanism, is being considered as a
therapeutic target in COVID‐19. Both, substitution of interferon and JAK/STAT inhibition to …

Role of miRNAs as biomarkers of COVID-19: A scoping review of the status and future directions for research in this field

MB Visacri, AS Nicoletti, EC Pincinato… - Biomarkers in …, 2021 - Future Medicine
Aim: miRNAs are potential biomarkers of several diseases. This review aimed to identify the
miRNAs that could serve as biomarkers of COVID-19. Materials & methods: A literature …

[HTML][HTML] Dissection of key factors correlating with H5N1 avian influenza virus driven inflammatory lung injury of chicken identified by single-cell analysis

M Dai, S Zhu, Z An, B You, Z Li, Y Yao, V Nair… - PLoS …, 2023 - journals.plos.org
Chicken lung is an important target organ of avian influenza virus (AIV) infection, and
different pathogenic virus strains lead to opposite prognosis. Using a single-cell RNA …

Circulating biomarkers of inflammaging as potential predictors of COVID-19 severe outcomes

J Sabbatinelli, G Matacchione, A Giuliani… - Mechanisms of Ageing …, 2022 - Elsevier
The COVID-19 pandemic caused by SARS-CoV-2 infection has been of unprecedented
clinical and socio-economic worldwide relevance. The case fatality rate for COVID-19 grows …

[HTML][HTML] SARS-CoV-2 may trigger inflammasome and pyroptosis in the central nervous system: a mechanistic view of neurotropism

A Sepehrinezhad, A Gorji, S Sahab Negah - Inflammopharmacology, 2021 - Springer
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can enter the central
nervous system and cause several neurological manifestations. Data from cerebrospinal …