Human viral oncogenesis: a cancer hallmarks analysis

EA Mesri, MA Feitelson, K Munger - Cell host & microbe, 2014 - cell.com
Approximately 12% of all human cancers are caused by oncoviruses. Human viral
oncogenesis is complex, and only a small percentage of the infected individuals develop …

Human viruses and cancer

A Morales-Sánchez, EM Fuentes-Pananá - Viruses, 2014 - mdpi.com
The first human tumor virus was discovered in the middle of the last century by Anthony
Epstein, Bert Achong and Yvonne Barr in African pediatric patients with Burkitt's lymphoma …

Human cytomegalovirus latency: approaching the Gordian knot

F Goodrum - Annual review of virology, 2016 - annualreviews.org
Herpesviruses have evolved exquisite virus-host interactions that co-opt or evade a number
of host pathways to enable the viruses to persist. Persistence of human cytomegalovirus …

EBV-miR-BART7-3p promotes the EMT and metastasis of nasopharyngeal carcinoma cells by suppressing the tumor suppressor PTEN

LM Cai, XM Lyu, WR Luo, XF Cui, YF Ye, CC Yuan… - Oncogene, 2015 - nature.com
The epithelial-mesenchymal transition (EMT) is crucial to cancer progression and
metastasis. Although multiple cellular miRNAs have been identified to regulate the EMT and …

Distinct viral and mutational spectrum of endemic Burkitt lymphoma

F Abate, MR Ambrosio, L Mundo, MA Laginestra… - PLoS …, 2015 - journals.plos.org
Endemic Burkitt lymphoma (eBL) is primarily found in children in equatorial regions and
represents the first historical example of a virus-associated human malignancy. Although …

[HTML][HTML] Calling in SYK: SYK's dual role as a tumor promoter and tumor suppressor in cancer

MO Krisenko, RL Geahlen - … et Biophysica Acta (BBA)-Molecular Cell …, 2015 - Elsevier
SYK (spleen tyrosine kinase) is well-characterized in the immune system as an essential
enzyme required for signaling through multiple classes of immune recognition receptors. As …

Cancers associated with human gammaherpesviruses

KW Wen, L Wang, JR Menke, B Damania - The FEBS journal, 2022 - Wiley Online Library
Epstein–Barr virus (EBV; human herpesvirus 4; HHV‐4) and Kaposi sarcoma‐associated
herpesvirus (KSHV; human herpesvirus 8; HHV‐8) are human gammaherpesviruses that …

Epstein–Barr virus-associated malignancies: Roles of viral oncoproteins in carcinogenesis

A El-Sharkawy, L Al Zaidan, A Malki - Frontiers in oncology, 2018 - frontiersin.org
The Epstein–Barr virus (EBV) is the first herpesvirus identified to be associated with human
cancers known to infect the majority of the world population. EBV-associated malignancies …

Epstein-Barr virus-encoded LMP2A induces an epithelial–mesenchymal transition and increases the number of side population stem-like cancer cells in …

QL Kong, LJ Hu, JY Cao, YJ Huang, LH Xu… - PLoS …, 2010 - journals.plos.org
It has been recently reported that a side population of cells in nasopharyngeal carcinoma
(NPC) displayed characteristics of stem-like cancer cells. However, the molecular …

Time-resolved transcriptomes reveal diverse B cell fate trajectories in the early response to Epstein-Barr virus infection

ED SoRelle, J Dai, NM Reinoso-Vizcaino, AP Barry… - Cell reports, 2022 - cell.com
Epstein-Barr virus infection of B lymphocytes elicits diverse host responses via well-adapted
transcriptional control dynamics. Consequently, this host-pathogen interaction provides a …