Natural killer (NK) cells, the large granular lymphocytes differentiated from the common
lymphoid progenitors, were discovered in early 1970's. They are members of innate …

Neuro-Behçet's disease (NBD) is one of the more serious manifestations of Behçet's disease
(BD), which is a relapsing inflammatory multisystem disease with an interesting …

Venous thromboembolism (VTE) is a significant contributor to morbidity and mortality. To
advance our understanding of the biology contributing to VTE, we conducted a genome …

Individuals with Behçet's disease suffer from episodic inflammation often affecting the
orogenital mucosa, skin and eyes. To discover new susceptibility loci for Behçet's disease …

Behçet's disease (BD) is a multisystem relapsing inflammatory disorder of unknown cause.
In neuro-BD (NBD), the CNS can be involved in one or both of two ways: first, and most …

OBJECTIVE:: Off-label use of anti-tumor necrosis factor (TNF) agents for Behçet's disease
(BD) is increasing. We evaluated published data on their efficacy and safety for patients with …

Objective Behçet's disease (BD) is a rare, multisystem inflammatory disorder of unknown
cause. Although well‐documented in Eastern populations, epidemiologic data is scarce in …

Background Behçet disease (BD) is an immune‐mediated vasculitis‐like syndrome
characterized by recurrent aphthous lesions and various systemic manifestations …

Venous thromboembolism (VTE) is major health problem and is sometimes complicated by
lethal pulmonary embolism (PE). Disturbances of the coagulation and anticoagulation …

Background The nuclear factor κ light-chain enhancer of activated B cells (NF-κB) signaling
pathway is a key regulator of immune responses. Accordingly, mutations in several NF-κB …