Targeting IL-6 trans-signalling: past, present and future prospects
S Rose-John, BJ Jenkins, C Garbers, JM Moll… - Nature Reviews …, 2023 - nature.com
Abstract Interleukin-6 (IL-6) is a key immunomodulatory cytokine that affects the
pathogenesis of diverse diseases, including autoimmune diseases, chronic inflammatory …
pathogenesis of diverse diseases, including autoimmune diseases, chronic inflammatory …
[PDF][PDF] COVID-19 and the human innate immune system
JL Schultze, AC Aschenbrenner - Cell, 2021 - cell.com
The introduction of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) into the
human population represents a tremendous medical and economic crisis. Innate immunity …
human population represents a tremendous medical and economic crisis. Innate immunity …
TLR3 and TLR7 RNA sensor activation during SARS-CoV-2 infection
(1) Background: Acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the etiological
agent for the coronavirus disease (COVID-19) that has led to a pandemic that began in …
agent for the coronavirus disease (COVID-19) that has led to a pandemic that began in …
Oral microbiome dysbiosis is associated with symptoms severity and local immune/inflammatory response in COVID-19 patients: a cross-sectional study
I Soffritti, M D'Accolti, C Fabbri, A Passaro… - Frontiers in …, 2021 - frontiersin.org
The human oral microbiome (HOM) is the second largest microbial community after the gut
and can impact the onset and progression of several localized and systemic diseases …
and can impact the onset and progression of several localized and systemic diseases …
Cascade of immune mechanism and consequences of inflammatory disorders
Inflammatory responses arise as an outcome of tissues or organs exposure towards harmful
stimuli like injury, toxic chemicals or pathogenic microorganism. It is a complex cascade of …
stimuli like injury, toxic chemicals or pathogenic microorganism. It is a complex cascade of …
Heart-rate-variability (HRV), predicts outcomes in COVID-19
MBA Mol, MTA Strous, FHM van Osch, FJ Vogelaar… - PloS one, 2021 - journals.plos.org
Background Patients with COVID-19 present with a variety of clinical manifestations, ranging
from mild or asymptomatic disease to severe illness and death. Whilst previous studies have …
from mild or asymptomatic disease to severe illness and death. Whilst previous studies have …
[HTML][HTML] Profiling of oral microbiota and cytokines in COVID-19 patients
The presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has been
recently demonstrated in the sputum or saliva, suggesting how the shedding of viral RNA …
recently demonstrated in the sputum or saliva, suggesting how the shedding of viral RNA …
[HTML][HTML] Identification of small molecule inhibitors of the deubiquitinating activity of the SARS-CoV-2 papain-like protease: in silico molecular docking studies and in …
COVID-19 is an ongoing pandemic caused by the SARS-CoV-2 virus with important political,
socio-economic, and public health consequences. Inhibiting replication represents an …
socio-economic, and public health consequences. Inhibiting replication represents an …
Immune-checkpoint inhibitors from cancer to COVID‑19: A promising avenue for the treatment of patients with COVID‑19
S Vivarelli, L Falzone, F Torino… - International …, 2021 - spandidos-publications.com
The severe acute respiratory syndrome associated coronavirus‑2 (SARS‑CoV‑2) poses a
threat to human life worldwide. Since early March, 2020, coronavirus disease 2019 (COVID …
threat to human life worldwide. Since early March, 2020, coronavirus disease 2019 (COVID …
Emerging electrochemical biosensing trends for rapid diagnosis of COVID-19 biomarkers as point-of-care platforms: A critical review
Rapid diagnosis is a critical aspect associated with controlling the spread of COVID-19.
Electrochemical sensor platforms are ideally suited for rapid and highly sensitive detection …
Electrochemical sensor platforms are ideally suited for rapid and highly sensitive detection …