The upward extend of malaria collectively with the emergence of resistance against
predictable drugs has put enormous pressure on public health systems to introduce new …

The biological activity of Mannich bases, a structurally heterogeneous class of chemical
compounds that are generated from various substrates through the introduction of an …

Antimalarial drugs with the 4-aminoquinoline scaffold such as the important drugs,
chloroquine (CQ) and amodiaquine (AQ), have been used to prevent and treat malaria for …

A short history of hybrid molecules based on aminoquinolines gave interesting and
important information useful for organic and medicinal chemistry, which are deeply involved …

Antimalarial drugs constitute a major part of antiprotozoal drugs and have been in practice
for a long time. Antimalarial agents generally belong to the class of quinoline which acts by …

Antimalarial drugs have played a mainstream role in controlling the spread of malaria
through the treatment of patients infected with the plasmodial parasites and controlling its …

Malaria has emerged as a major health problem worldwide after the appearance of resistant
strains of Plasmodium falciparum to the most of antimalarial drugs. The development of …

According to the World Health Organization, half of the World's population, approximately
3.3 billion people, is at risk for developing malaria. Nearly 700,000 deaths each year are …

Malaria continues to be an important public health problem in the world. Nowadays, the
widespread parasite resistance to many drugs used in antimalarial therapy has made the …

Malaria represents a significant health issue, and novel effective drugs are needed to
address parasite resistance that has emerged to the current drug arsenal. The most popular …