Multifaceted highly targeted sequential multidrug treatment of early ambulatory high-risk SARS-CoV-2 infection (COVID-19)

PA McCullough, PE Alexander… - Reviews in …, 2020 - scholarlycommons.henryford.com
The SARS-CoV-2 virus spreading across the world has led to surges of COVID-19 illness,
hospitalizations, and death. The complex and multifaceted pathophysiology of life …

[HTML][HTML] Evidence regarding vitamin D and risk of COVID-19 and its severity

J Mercola, WB Grant, CL Wagner - Nutrients, 2020 - mdpi.com
Vitamin D deficiency co-exists in patients with COVID-19. At this time, dark skin color,
increased age, the presence of pre-existing illnesses and vitamin D deficiency are features …

[HTML][HTML] Persistent clotting protein pathology in Long COVID/Post-Acute Sequelae of COVID-19 (PASC) is accompanied by increased levels of antiplasmin

E Pretorius, M Vlok, C Venter, JA Bezuidenhout… - Cardiovascular …, 2021 - Springer
Background Severe acute respiratory syndrome coronavirus 2 (SARS-Cov-2)-induced
infection, the cause of coronavirus disease 2019 (COVID-19), is characterized by acute …

[HTML][HTML] SARS-CoV-2 crosses the blood–brain barrier accompanied with basement membrane disruption without tight junctions alteration

L Zhang, L Zhou, L Bao, J Liu, H Zhu, Q Lv… - Signal transduction and …, 2021 - nature.com
SARS-CoV-2 has been reported to show a capacity for invading the brains of humans and
model animals. However, it remains unclear whether and how SARS-CoV-2 crosses the …

[HTML][HTML] COVCOG 2: cognitive and memory deficits in long COVID: a second publication from the COVID and cognition study

P Guo, A Benito Ballesteros, SP Yeung… - Frontiers in aging …, 2022 - frontiersin.org
COVID-19, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has
been often characterized as a respiratory disease. However, it is increasingly being …

[HTML][HTML] SARS-CoV-2 spike protein induces degradation of junctional proteins that maintain endothelial barrier integrity

S Raghavan, DB Kenchappa, MD Leo - Frontiers in cardiovascular …, 2021 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) uses the Angiotensin
converting enzyme 2 (ACE-2) receptor present on the cell surface to enter cells. ACE-2 is …

[HTML][HTML] Cytokine storm and histopathological findings in 60 cases of COVID-19-related death: from viral load research to immunohistochemical quantification of major …

P Frisoni, M Neri, S D'Errico, L Alfieri… - … Science, Medicine and …, 2022 - Springer
This study involves the histological analysis of samples taken during autopsies in cases of
COVID-19 related death to evaluate the inflammatory cytokine response and the tissue …

[HTML][HTML] Vascular endothelial glycocalyx damage in COVID-19

M Yamaoka-Tojo - International Journal of Molecular Sciences, 2020 - mdpi.com
The new coronavirus disease-2019 (COVID-19), which is spreading around the world and
threatening people, is easily infecting a large number of people through airborne droplets; …

[HTML][HTML] Vanadium as potential therapeutic agent for COVID-19: A focus on its antiviral, antiinflamatory, and antihyperglycemic effects

S Semiz - Journal of Trace Elements in Medicine and Biology, 2022 - Elsevier
An increasing evidence suggests that vanadium compounds are novel potential drugs in the
treatment of diabetes, atherosclerosis, and cancer. Vanadium has also demonstrated …

[HTML][HTML] The manifold cellular functions of von willebrand factor

A Mojzisch, MA Brehm - Cells, 2021 - mdpi.com
The plasma glycoprotein von Willebrand factor (VWF) is exclusively synthesized in
endothelial cells (ECs) and megakaryocytes, the precursor cells of platelets. Its primary …