[HTML][HTML] Structural and functional properties of SARS-CoV-2 spike protein: potential antivirus drug development for COVID-19

Y Huang, C Yang, X Xu, W Xu, S Liu - Acta Pharmacologica Sinica, 2020 - nature.com
Coronavirus disease 2019 is a newly emerging infectious disease currently spreading
across the world. It is caused by a novel coronavirus, severe acute respiratory syndrome …

COVID-19 Vaccine: A comprehensive status report

SP Kaur, V Gupta - Virus research, 2020 - Elsevier
The current COVID-19 pandemic has urged the scientific community internationally to find
answers in terms of therapeutics and vaccines to control SARS-CoV-2. Published …

Optimization of lipid nanoparticles for the delivery of nebulized therapeutic mRNA to the lungs

MP Lokugamage, D Vanover, J Beyersdorf… - Nature biomedical …, 2021 - nature.com
Lipid nanoparticles (LNPs) for the efficient delivery of drugs need to be designed for the
particular administration route and type of drug. Here we report the design of LNPs for the …

Efficacy and safety of COVID-19 vaccines: a systematic review and meta-analysis of randomized clinical trials

A Pormohammad, M Zarei, S Ghorbani, M Mohammadi… - Vaccines, 2021 - mdpi.com
The current study systematically reviewed, summarized and meta-analyzed the clinical
features of the vaccines in clinical trials to provide a better estimate of their efficacy, side …

The emergence of COVID-19 as a global pandemic: Understanding the epidemiology, immune response and potential therapeutic targets of SARS-CoV-2

S Muralidar, SV Ambi, S Sekaran, UM Krishnan - Biochimie, 2020 - Elsevier
An acute respiratory disease caused by a severe acute respiratory syndrome coronavirus 2
(SARS-CoV-2) that surfaced in China in late 2019, continues to spread rapidly across the …

Vaccine hesitancy in the era of COVID-19

G Troiano, A Nardi - Public health, 2021 - Elsevier
Objectives In 2019, a new coronavirus has been identified and many efforts have been
directed toward the development of effective vaccines. However, the willingness for …

Development of an inactivated vaccine candidate for SARS-CoV-2

Q Gao, L Bao, H Mao, L Wang, K Xu, M Yang, Y Li… - Science, 2020 - science.org
The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has resulted in an unprecedented public health …

Immune-mediated approaches against COVID-19

HF Florindo, R Kleiner, D Vaskovich-Koubi… - Nature …, 2020 - nature.com
Abstract The coronavirus disease-19 (COVID-19) is caused by the severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2). The long incubation period of this new virus, which …

Predictors of adverse prognosis in COVID‐19: a systematic review and meta‐analysis

S Figliozzi, PG Masci, N Ahmadi, L Tondi… - European journal of …, 2020 - Wiley Online Library
Background Identification of reliable outcome predictors in coronavirus disease 2019
(COVID‐19) is of paramount importance for improving patient's management. Methods A …

Human leukocyte antigen susceptibility map for severe acute respiratory syndrome coronavirus 2

A Nguyen, JK David, SK Maden, MA Wood… - Journal of …, 2020 - Am Soc Microbiol
Genetic variability across the three major histocompatibility complex (MHC) class I genes
(human leukocyte antigen A [HLA-A],-B, and-C genes) may affect susceptibility to and …