In metastatic breast cancer (MBC), the conventional doxorubicin (DOX) has various
problems due to lack of selectivity with subsequent therapeutic failure and adverse effects …

Conventional cytotoxic cancer chemotherapy is often immunosuppressive and associated
with drug resistance and tumor regrowth after a short period of tumor shrinkage or growth …

Canine mammary tumors (CMTs) are the most common neoplasm in intact female dogs.
Canine mammary cancer (CMC) represents 50% of CMTs, and besides surgery, which is the …

The anti-tumor activity of the immune system is increasingly recognized as critical for the
mounting of a prolonged and effective response to cancer growth and invasion, and for …

Drug delivery systems are developed to maximize drug efficacy and minimize side effects.
As drug delivery technologies improve, the drug becomes safer and more comfortable for …

Systemic chemotherapy given at maximum tolerated doses (MTD) has been the mainstay of
cancer treatment for more than half a century. In some chemosensitive diseases such as …

Immune checkpoint inhibitor therapy has revolutionized the field of cancer immunotherapy.
Even though it has shown a durable response in some solid tumors, several patients do not …

Background/Aims: LncRNAs have been reported to be vital regulators of the progression of
osteosarcoma, although the underlying mechanisms are not completely understood …

Background Neuroblastoma (NB) is the most common cancer in infancy and most frequent
cause of death from extracranial solid tumors in children. Ornithine decarboxylase (ODC) …

Although neoantigen-based cancer vaccines show great potential in cancer immunotherapy
due to their ability to induce effective and long-lasting anti-tumor immunity, their …