Inflammation-induced osteogenesis in a rabbit tibia model

M Croes, W Boot, MC Kruyt, H Weinans… - … Engineering Part C …, 2017 - liebertpub.com
Pathologic conditions associated with bone formation can serve as models to identify bone-
promoting mediators. The inflammatory response to bacterial infections generally leads to …

From brain to bone: evidence for the release of osteogenic humoral factors after traumatic brain injury

AM Toffoli, OP Gautschi, SP Frey, L Filgueira… - Brain Injury, 2008 - Taylor & Francis
Primary objective: The aetiology of the increased osteogenesis associated with severe
traumatic brain injury (TBI) remains incompletely understood. The purpose of this article is to …

The function of proprioceptors in bone organization: a possible explanation for neurogenic heterotopic ossification in patients with neurological damage

AC da Paz, FJC Artal, RK Kalil - Medical hypotheses, 2007 - Elsevier
Neurogenic heterotopic ossification is characterized by the formation of extra osseous bone
in soft tissue surrounding peripheral joints in neurological patients. It occurs in 25% of spinal …

[HTML][HTML] Heterotopic ossification in a 7‐year‐old female patient treated with individualized homeopathy: A case report

D Tsintzas, A Jaggi, L Jaggi, S Mahesh… - Clinical Case …, 2019 - ncbi.nlm.nih.gov
We present a case report of a seven‐year‐old girl suffering from severe congenital
heterotopic ossification. The patient received treatment with individualized remedies …

[HTML][HTML] Matrine attenuates heterotopic ossification by suppressing TGF-β induced mesenchymal stromal cell migration and osteogenic differentiation

D Mao, X Pan, Y Rui, F Li - Biomedicine & Pharmacotherapy, 2020 - Elsevier
Purpose of the study Heterotopic ossification (HO) is a debilitating disease characterized by
extraskeletal bone formation. Active TGF-β recruits mesenchymal stromal cells (MSCs) …

Identification of risk factors in the development of heterotopic ossification after primary total hip arthroplasty

S Singh, S Morshed, D Motamedi… - The Journal of …, 2022 - academic.oup.com
Purpose Heterotopic ossification (HO) is a process by which bone forms abnormally in soft
tissues. Known risk factors for developing HO include male sex, spinal cord injury, trauma …

[PDF][PDF] Long-term orthopedic manifestations of COVID-19: Heterotopic ossification and digital necrosis

J Liu, L Luther, S Dwivedi, AR Evans - RI Med J, 2022 - rimed.org
Despite its classification as an atypical pneumonia, COVID-19 is a disease that is capable of
inflicting damage beyond the respiratory system. The wide range of musculoskeletal …

[PDF][PDF] What triggers cell-mediated mineralization

LF Huitema, AB Vaandrager - Front Biosci, 2007 - researchgate.net
Mineralization is an essential requirement for normal skeletal development, which is
generally accomplished through the function of two cell types, osteoblasts and chondrocytes …

Palovarotene inhibits connective tissue progenitor cell proliferation in a rat model of combat‐related heterotopic ossification

BM Wheatley, KE Cilwa, D Dey… - Journal of …, 2018 - Wiley Online Library
Heterotopic ossification (HO) develops in the extremities of wounded service members and
is common in the setting of high‐energy penetrating injuries and blast‐related amputations …

Heterotopic ossification after stroke: clinical profile and severity of ossification

D de Aquino Cunha, S Camargos… - Journal of Stroke and …, 2019 - Elsevier
Background and purpose: The aim of this study was to evaluate heterotopic ossification (HO)
prevalence after stroke, describing clinical features and investigating predictors of HO and …