Continuous and discontinuous RNA synthesis in coronaviruses

I Sola, F Almazán, S Zúñiga… - Annual review of …, 2015 - annualreviews.org
Replication of the coronavirus genome requires continuous RNA synthesis, whereas
transcription is a discontinuous process unique among RNA viruses. Transcription includes …

Porcine reproductive and respiratory syndrome virus (PRRSV): pathogenesis and interaction with the immune system

JK Lunney, Y Fang, A Ladinig, N Chen… - Annual review of …, 2016 - annualreviews.org
This review addresses important issues of porcine reproductive and respiratory syndrome
virus (PRRSV) infection, immunity, pathogenesis, and control. Worldwide, PRRS is the most …

Porcine reproductive and respiratory syndrome viruses (porcine arteriviruses)

JJ Zimmerman, SA Dee, DJ Holtkamp… - Diseases of …, 2019 - Wiley Online Library
Control of porcine reproductive and respiratory syndrome virus (PRRSV) remains
problematic, and economic studies have uniformly shown that PRRSV inflicts major losses …

Improved vaccine against PRRSV: current progress and future perspective

Y Nan, C Wu, G Gu, W Sun, YJ Zhang… - Frontiers in …, 2017 - frontiersin.org
Porcine reproductive and respiratory syndrome virus (PRRSV), one of the most
economically significant pathogens worldwide, has caused numerous outbreaks during the …

Arterivirus molecular biology and pathogenesis

EJ Snijder, M Kikkert, Y Fang - Journal of General …, 2013 - microbiologyresearch.org
Arteriviruses are positive-stranded RNA viruses that infect mammals. They can cause
persistent or asymptomatic infections, but also acute disease associated with a respiratory …

The PRRSV replicase: exploring the multifunctionality of an intriguing set of nonstructural proteins

Y Fang, EJ Snijder - Virus research, 2010 - Elsevier
Our knowledge about the structure and function of the nonstructural proteins (nsps) encoded
by the arterivirus replicase gene has advanced in recent years. The continued …

Molecular and cellular mechanisms for PRRSV pathogenesis and host response to infection

TQ An, JN Li, CM Su, D Yoo - Virus research, 2020 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) has caused tremendous
amounts of economic losses to the swine industry for more than three decades, but its …

Immunological solutions for treatment and prevention of porcine reproductive and respiratory syndrome (PRRS)

MP Murtaugh, M Genzow - Vaccine, 2011 - Elsevier
Vaccination is the principal means used to control and treat porcine reproductive and
respiratory syndrome virus (PRRSV) infection. An array of PRRS vaccine products is …

The cysteine protease domain of porcine reproductive and respiratory syndrome virus nonstructural protein 2 possesses deubiquitinating and interferon antagonism …

Z Sun, Z Chen, SR Lawson, Y Fang - Journal of virology, 2010 - Am Soc Microbiol
Porcine reproductive and respiratory syndrome (PRRS) virus nonstructural protein 2 (nsp2)
contains a cysteine protease domain at its N terminus, which belongs to the ovarian tumor …

Pathogenesis of porcine reproductive and respiratory syndrome virus

RJ Chand, BR Trible, RRR Rowland - Current opinion in virology, 2012 - Elsevier
Porcine reproductive and respiratory syndrome virus (PRRSV) is the most costly viral
pathogen facing a modern pig industry. A unique feature of the virus is the ability to cause …