Severe acute pancreatitis (SAP) is a severe disease with a high prevalence and a 3‑15%
mortality worldwide, and premature activation of zymogen for any reason is the initial factor …

Systemic inflammation includes a widespread immune response to a harmful stimulus that
results in extensive systemic damage. One common example of systemic inflammation is …

The present study was a prospective observational single center study, enrolling 102
patients with sepsis, admitted in the Intensive Care Unit of the County Emergency Clinical …

Introduction Exploring monocytes' roles within the tumor microenvironment is crucial for
crafting targeted cancer treatments. Methods This study unveils a novel methodology …

Sepsis is a clinical syndrome caused by uncontrollable immune dysregulation triggered by
pathogen infection, characterized by high incidence, mortality rates, and disease burden …

Sepsis-induced acute kidney injury (S-AKI) is one of the most serious life-threatening
complications of sepsis. The pathogenesis of S-AKI is complex and there is no effective …

Immune alterations in end-stage renal patients receiving hemodialysis are complex and
predispose patients to infections. Anticoagulation may also play an immunomodulatory role …

Sepsis is a dysregulated host response to severe infections, and immune dysfunction plays
a crucial role in its pathogenesis. Elderly patients, a special population influenced by …

Purpose Immune dysfunction plays a pivotal role in sepsis pathogenesis. Previous studies
have revealed the crucial role of T cells and human leukocyte antigen-DR (HLA-DR) in …

Objective This study aimed to link intracellular adenosine triphosphate content in CD4+ T
lymphocytes (CD4+ iATP) with sepsis patient mortality, seeking a new predictive biomarker …