High‐dimensional hypothesis testing is ubiquitous in the biomedical sciences, and
informative covariates may be employed to improve power. The conditional false discovery …

Objectives: Clinical and epidemiological findings indicate an association between coronary
artery disease (CAD) and low birth weight (BW). However, the mechanisms underlying this …

Background Genome-wide association studies (GWASs) routinely identify loci associated
with risk factors for osteoporosis. However, GWASs with relatively small sample sizes still …

An increasing number of epidemiological studies have suggested that birth weight (BW) may
be a determinant of bone health later in life, although the underlying genetic mechanism …

Adiposity has been associated with the risk of coronary artery disease (CAD) in
observational studies, but their association may differ according to specific characteristics of …

Genome-wide association studies (GWAS) have been shown to have the potential of
explaining more of the “missing heritability” of complex human phenotypes by improving …

Obesity is one of the major challenges in modern society. More than a third of the world's
population suffers froms overweight. This phenotype affects the quality of life and is …

Background Epidemiological and clinical investigations have established a robust
correlation between Cancer and Heart Failure, with patients afflicted by either condition …

Objective To estimate the correlation between indices of diet quality (DQIs), insulin
sensitivity (QUICKI) and resistance (HOMA-IR), waist circumference (WHR) and body mass …

Ожирение становится одной из глобальных проблем–более трети мирового населения
имеют избыточный вес. Эта патология существенно влияет на качество жизни и …