Promising antiviral activities of natural flavonoids against SARS-CoV-2 targets: systematic review

R Kaul, P Paul, S Kumar, D Büsselberg… - International journal of …, 2021 - mdpi.com
The ongoing COVID-19 pandemic, caused by the severe acute respiratory syndrome
coronavirus 2 (SARS-CoV-2) became a globally leading public health concern over the past …

[HTML][HTML] Inhibition of the main protease of SARS-CoV-2 (Mpro) by repurposing/designing drug-like substances and utilizing nature's toolbox of bioactive compounds

I Antonopoulou, E Sapountzaki, U Rova… - Computational and …, 2022 - Elsevier
The emergence of the Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)
has resulted in a long pandemic, with numerous cases and victims worldwide and enormous …

One-pot synthesis and molecular modeling studies of new bioactive spiro-oxindoles based on uracil derivatives as SARS-CoV-2 inhibitors targeting RNA polymerase …

SA El-Kalyoubi, A Ragab, OA Abu Ali, YA Ammar… - Pharmaceuticals, 2022 - mdpi.com
The first outbreak in Wuhan, China, in December 2019 was reported about severe acute
coronaviral syndrome 2 (SARS-CoV-2). The global coronavirus disease 2019 (COVID-19) …

Glycyrrhizin as a promising kryptonite against SARS-CoV-2: Clinical, experimental, and theoretical evidences

S Banerjee, SK Baidya, N Adhikari, B Ghosh… - Journal of Molecular …, 2023 - Elsevier
COVID-19 is the most devastating disease in recent times affecting most people globally.
The higher rate of transmissibility and mutations of SARS-CoV-2 along with the lack of …

Evaluation of antimicrobial, anticholinesterase potential of indole derivatives and unexpectedly synthesized novel benzodiazine: characterization, DFT and Hirshfeld …

AR Raza, SL Rubab, M Ashfaq, Y Altaf, MN Tahir… - Molecules, 2023 - mdpi.com
The pharmacological effectiveness of indoles, benzoxazepines and benzodiazepines
initiated our synthesis of indole fused benoxazepine/benzodiazepine heterocycles, along …

Traditional uses, pharmacological effects, and molecular mechanisms of licorice in potential therapy of COVID-19

Q Zhang, H Huang, M Qiu, Z Wu, Z Xin, X Cai… - Frontiers in …, 2021 - frontiersin.org
The current Coronavirus disease 2019 (COVID-19) pandemic has become a global
challenge, and although vaccines have been developed, it is expected that mild to moderate …

An overview of anti-SARS-CoV-2 and anti-inflammatory potential of baicalein and its metabolite baicalin: insights into molecular mechanisms

B Dinda, M Dinda, S Dinda, UC De - European Journal of Medicinal …, 2023 - Elsevier
Abstract The current Coronavirus Disease 2019 (COVID-19) pandemic, caused by the
Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2), is highly contagious …

Synthesis, Crystal Structure, DFT Calculations, Hirshfeld Surface Analysis and In Silico Drug-Target Profiling of (R)-2-(2-(1,3-Dioxoisoindolin-2-yl)propanamido) …

SL Rubab, AR Raza, B Nisar, M Ashfaq, Y Altaf… - Molecules, 2023 - mdpi.com
The work here reflects synthesis, DFT studies, Hirshfeld charge analysis and crystal data
exploration of pharmacologically important (R)-2-(2-(1, 3-dioxoisoindolin-2-yl) propanamido) …

The main protease of SARS-CoV-2 as a target for phytochemicals against coronavirus

SS Issa, SV Sokornova, RR Zhidkin, TV Matveeva - Plants, 2022 - mdpi.com
In late December 2019, the first cases of COVID-19 emerged as an outbreak in Wuhan,
China that later spread vastly around the world, evolving into a pandemic and one of the …

[HTML][HTML] Advances in pathogenesis, progression, potential targets and targeted therapeutic strategies in SARS-CoV-2-Induced COVID-19

H Zhou, WJ Ni, W Huang, Z Wang, M Cai… - Frontiers in …, 2022 - frontiersin.org
As the new year of 2020 approaches, an acute respiratory disease quietly caused by severe
acute respiratory syndrome coronavirus 2 (SARS-CoV-2), also known as coronavirus …