Availability of oral antivirals against SARS-CoV-2 infection and the requirement for an ethical prescribing approach

R Dal-Ré, SL Becker, E Bottieau… - The Lancet Infectious …, 2022 - thelancet.com
The first two oral antivirals, molnupiravir and nirmatrelvir–ritonavir, are now becoming
available in many countries. These medicines will be indicated to treat mild-to-moderate …

[HTML][HTML] Prevalence of COVID-19-associated pulmonary aspergillosis: critical review and conclusions

M Egger, L Bussini, M Hoenigl, M Bartoletti - Journal of Fungi, 2022 - mdpi.com
First reports of cases and case series of COVID-19-associated pulmonary aspergillosis
(CAPA) emerged during the first months of the pandemic. Prevalence rates varied widely …

[HTML][HTML] The intersection of obesity and (long) COVID-19: Hypoxia, thrombotic inflammation, and vascular endothelial injury

M Xiang, X Wu, H Jing, VA Novakovic… - Frontiers in …, 2023 - frontiersin.org
The role of hypoxia, vascular endothelial injury, and thrombotic inflammation in worsening
COVID-19 symptoms has been generally recognized. Damaged vascular endothelium plays …

Outcome of early treatment of SARS‐CoV‐2 infection in patients with haematological disorders

M Mikulska, D Testi, C Russo, E Balletto… - British Journal of …, 2023 - Wiley Online Library
Outcome of early treatment of COVID‐19 with antivirals or anti‐spike monoclonal antibodies
(MABs) in patients with haematological malignancies (HM) is unknown. A retrospective …

[HTML][HTML] Risk factors and effect on mortality of superinfections in a newly established COVID-19 respiratory sub-intensive care unit at University Hospital in Rome

A Iacovelli, A Oliva, G Siccardi, A Tramontano… - BMC Pulmonary …, 2023 - Springer
Background Little is known on the burden of co-infections and superinfections in a specific
setting such as the respiratory COVID-19 sub-intensive care unit. This study aims to (i) …

Drug treatment of COVID-19 infection

G Lui, G Guaraldi - Current Opinion in Pulmonary Medicine, 2023 - journals.lww.com
Drug treatment of COVID-19 infection : Current Opinion in Pulmonary Medicine Drug treatment
of COVID-19 infection : Current Opinion in Pulmonary Medicine Log in or Register Subscribe to …

[HTML][HTML] Colchicine and the combination of rivaroxaban and aspirin in patients hospitalised with COVID-19 (ACT): an open-label, factorial, randomised, controlled trial

JW Eikelboom, SS Jolly, EP Belley-Cote… - The Lancet …, 2022 - thelancet.com
Background COVID-19 disease is accompanied by a dysregulated immune response and
hypercoagulability. The Anti-Coronavirus Therapies (ACT) inpatient trial aimed to evaluate …

[HTML][HTML] Major candidate variables to guide personalised treatment with steroids in critically ill patients with COVID-19: CIBERESUCICOVID study

A Torres, A Motos, C Cillóniz, A Ceccato… - Intensive care …, 2022 - Springer
Purpose Although there is evidence supporting the benefits of corticosteroids in patients
affected with severe coronavirus disease 2019 (COVID-19), there is little information related …

[HTML][HTML] Remdesivir: a review in COVID-19

HA Blair - Drugs, 2023 - Springer
Remdesivir (Veklury®), a nucleotide analogue prodrug with broad-spectrum antiviral activity,
is approved for the treatment of coronavirus disease 2019 (COVID-19), the illness caused by …

Efficacy and safety of corticosteroid therapy for community-acquired pneumonia: a meta-analysis and meta-regression of randomized, controlled trials

F Bergmann, L Pracher, R Sawodny… - Clinical Infectious …, 2023 - academic.oup.com
Background Community-acquired pneumonia (CAP) is associated with high morbidity and
mortality. In the present study, we aimed to assess the effect of corticosteroids on all-cause …