[HTML][HTML] Cerebral palsy and related neuromotor disorders: Overview of genetic and genomic studies

JM Friedman, P van Essen… - Molecular genetics and …, 2022 - Elsevier
Cerebral palsy (CP) is a debilitating condition characterized by abnormal movement or
posture, beginning early in development. Early family and twin studies and more recent …

Drug‐resistant epilepsy: drug target hypothesis and beyond the receptors

D Fonseca‐Barriendos, CL Frías‐Soria… - Epilepsia …, 2022 - Wiley Online Library
Epilepsy is a chronic neurological disorder that affects more than 50 million people
worldwide. Despite a recent introduction of antiseizure drugs for the treatment of epileptic …

[HTML][HTML] Effects of Environmental Factors and Epigenetic on Health and the Development of Diseases

M Farrokhi, F Taheri, E Karami, R Khorram… - Kindle, 2023 - preferpub.org
The effects of environmental factors and epigenetics on health and disease development
are complex and interconnected. Environmental factors encompass external influences like …

Gene therapy for hair cell regeneration: Review and new data

SB Shibata, MB West, X Du, Y Iwasa, Y Raphael… - Hearing Research, 2020 - Elsevier
Hair cells (HCs) in the cochlea are responsible for transducing mechanical sound energy
into neural impulses which lead to the perception of sound. Loss of these sensory cells is the …

Neurobiological systems in dyslexia

JR Kershner - Trends in neuroscience and education, 2019 - Elsevier
Biological systems-level principles of the genetic landscape underlying the neurobiology of
dyslexia provide a novel and heuristic theoretical framework for a new understanding of the …

Epigenetics in inflammatory breast cancer: biological features and therapeutic perspectives

FLC Faldoni, CA Rainho, SR Rogatto - Cells, 2020 - mdpi.com
Evidence has emerged implicating epigenetic alterations in inflammatory breast cancer
(IBC) origin and progression. IBC is a rare and rapidly progressing disease, considered the …

Epigenetic modifications and their potential contribution to traumatic brain injury pathobiology and outcome

L Zima, R West, P Smolen, N Kobori… - Journal of …, 2022 - liebertpub.com
Epigenetic information is not permanently encoded in the DNA sequence, but rather consists
of reversible, heritable modifications that regulate the gene expression profile of a cell …

Neuroepigenetic consequences of adolescent ethanol exposure

E Brocato, JT Wolstenholme - International Review of Neurobiology, 2021 - Elsevier
Adolescence is a critical developmental period characterized by ongoing brain maturation
processes including myelination and synaptic pruning. Adolescents experience heightened …

[HTML][HTML] miRNA nanoencapsulation to regulate the programming of the blood-brain barrier permeability by hypoxia

EG Figueroa, A Caballero-Román, JR Ticó… - Current Research in …, 2022 - Elsevier
Central nervous system (CNS)-related diseases are difficult to treat as most therapeutic
agents they cannot reach the brain tissue, mainly due to the blood-brain barrier (BBB) …

Integrative Multi-Omics Research in Cerebral Palsy: Current Progress and Future Prospects

C Xin, X Guan, L Wang, J Liu - Neurochemical Research, 2023 - Springer
Cerebral palsy (CP) describes a heterogeneous group of non-progressive
neurodevelopmental disorders affecting movement and posture. The etiology and diagnostic …