The psychological construct known as 'wellbeing'is an essential aspect of mental health,
above and beyond the absence of mental illness. As a complex concept, wellbeing has …

It has been postulated that rare coding variants (RVs; MAF< 0.01) contribute to the “missing”
heritability of complex traits. We developed a novel framework, the Rare variant heritability …

Current methods to evaluate gene-by-environment (GxE) interactions on biobank-scale
datasets are limited. MonsterLM enables multiple linear regression on genome-wide …

Objective: Genome-wide association studies (GWAS) have revolutionized our
understanding of the genetic basis of diseases by examining millions of genetic variants …

Genome-wide association studies (GWAS) have identified thousands of genetic variants
associated with complex traits. Many complex traits and diseases share common genetic …

Understanding the genetic architecture of complex traits is a central goal of modern human
genetics. Recent efforts focused on building large-scale biobanks, that collect genetic and …

Faktor genetik pada pewarisan bobot hidup ternak adalah nilai pemuliaan, deviasi
dominansi dan heritabilitas. Penelitian ini bertujuan mengidentifikasi komponen genotipe …

The ever more complex and larger datasets that statisticians can routinely access have
prompted the modi cation of traditional statistical methodology. Notably, genomic data have …

In recent decades statistical genetics has contributed substantially to our knowledge of
human health and biology. This research has many facets: from collecting data, to cleaning …

A major finding from the last decade of genome-wide association studies (GWAS) is that
variant-phenotype associations are significantly enriched in noncoding regulatory regions of …