Individuals at ultra-high risk (UHR) of psychosis are characterised by the emergence of
attenuated psychotic symptoms and deterioration in functioning. In view of the high non …

The schizophrenia spectrum has been a long-time concept and includes conditions that are
related genetically and phenomenologically to schizophrenia, such as schizoaffective …

Previous studies have revealed that brain-derived neurotrophic factor (BDNF) levels are
inversely associated with the severity of depressive symptoms. In addition, serum BDNF …

Cognitive deficits are known to be related to most forms of psychopathology. Here, we
perform local genetic correlation analysis as a means of identifying independent segments …

Introduction Clinical high risk for psychosis (CHR) is associated with mild cognitive
impairments. Symptoms are clustered into positive, negative and disorganization symptoms …

Abstract Background and Hypothesis Processing speed dysfunction is a core feature of
psychosis and predictive of conversion in individuals at clinical high risk (CHR) for …

Background There is limited evidence on the use of antipsychotics in patients with early-
onset schizophrenia, which lags significantly behind the studies on adult patients' …

In recent decades, clinicians have developed the construct of ultra-high risk (UHR) for
psychosis to characterize the prodromal phase of psychosis or classify people with weakly …

To elucidate the specific and shared genetic background of schizophrenia (SCZ) and bipolar
disorder (BPD) to better understand their nosology, this study explored the independent and …

Abstract Background Cognitive Remediation (CR) is designed to halt the pathological neural
systems that characterize major psychotic disorders (MPD), and its main objective is to …