Type 1 diabetes mellitus (T1DM) is the archetypal example of a T cell‐mediated
autoimmune disease characterized by selective destruction of pancreatic β cells. The …

The identification of diabetes-relevant islet autoantibodies is essential for predicting and
preventing type 1 diabetes (T1D). The aim of the current study was to evaluate a newly …

OBJECTIVE To examine duration of breastfeeding and timing of complementary foods and
risk of islet autoimmunity (IA). RESEARCH DESIGN AND METHODS The Environmental …

OBJECTIVE To investigate gastrointestinal infection episodes (GIEs) in relation to the
appearance of islet autoantibodies in The Environmental Determinants of Diabetes in the …

Islet autoantibodies are predominantly measured by radioassay to facilitate risk assessment
and diagnosis of type 1 diabetes. However, the reliance on radioactive components, large …

Objective The Environmental Determinants of Diabetes in the Young (TEDDY) study is
designed to identify environmental exposures triggering islet autoimmunity and type 1 …

OBJECTIVE We sought to evaluate costs associated with public health screening for
presymptomatic type 1 diabetes in 90,632 children as part of the Fr1da study in Bavaria and …

Aims/hypothesis Adult-onset type 1 diabetes, in which the 65 kDa isoform of GAD (GAD65)
is a major autoantigen, has a broad clinical phenotype encompassing variable need for …

Traditional linkage analysis and genome-wide association studies have identified HLA and
a number of non-HLA genes as genetic factors for islet autoimmunity (IA) and type 1 …

Harmonization of biomarkers is important for the comparability of laboratory results as it
allows the definition of universal reference values and clinical decision limits. In diabetology …