Emerging technologies for molecular diagnosis of sepsis

M Sinha, J Jupe, H Mack, TP Coleman… - Clinical microbiology …, 2018 - Am Soc Microbiol
Rapid and accurate profiling of infection-causing pathogens remains a significant challenge
in modern health care. Despite advances in molecular diagnostic techniques, blood culture …

How to optimize the use of blood cultures for the diagnosis of bloodstream infections? A state-of-the art

B Lamy, S Dargère, MC Arendrup, JJ Parienti… - Frontiers in …, 2016 - frontiersin.org
Bloodstream infection (BSI) is a major cause of death in developed countries and the
detection of microorganisms is essential in managing patients. Despite major progress has …

Surviving sepsis campaign: international guidelines for management of sepsis and septic shock: 2016

A Rhodes, LE Evans, W Alhazzani, MM Levy… - Intensive care …, 2017 - Springer
Objective To provide an update to “Surviving Sepsis Campaign Guidelines for Management
of Sepsis and Septic Shock: 2012”. Design A consensus committee of 55 international …

Practical guidance for clinical microbiology laboratories: a comprehensive update on the problem of blood culture contamination and a discussion of methods for …

GV Doern, KC Carroll, DJ Diekema… - Clinical microbiology …, 2019 - Am Soc Microbiol
In this review, we present a comprehensive discussion of matters related to the problem of
blood culture contamination. Issues addressed include the scope and magnitude of the …

[HTML][HTML] Contaminants in blood cultures: importance, implications, interpretation and prevention

S Dargère, H Cormier, R Verdon - Clinical Microbiology and Infection, 2018 - Elsevier
Background Despite the development of new microbiologic technologies, blood cultures
(BCs) remain the first-line tool for the diagnosis of bloodstream infections. Their diagnostic …

Diagnosis and treatment of catheter-related bloodstream infection: Clinical guidelines of the Spanish Society of Infectious Diseases and Clinical Microbiology and …

F Chaves, J Garnacho-Montero, JL Del Pozo, E Bouza… - Medicina intensiva, 2018 - Elsevier
Catheter-related bloodstream infections (CRBSI) constitute an important cause of hospital-
acquired infection associated with morbidity, mortality, and cost. The aim of these guidelines …

[PDF][PDF] S3-leitlinie sepsis–prävention, diagnose, therapie und nachsorge

FM Brunkhorst, MA Weigand, M Pletz… - 2020 - publications.goettingen-research …
BeieinerSepsishandeltessichumeinelebens… Organdysfunktion ausgelöst durch eine
Infektion, die mit einer Regulationsstörung beim Wirt einhergeht. Ähnlich wie bei …

The impact of coronavirus disease 2019 (COVID-19) response on central-line–associated bloodstream infections and blood culture contamination rates at a tertiary …

J LeRose, A Sandhu, J Polistico, J Ellsworth… - Infection Control & …, 2021 - cambridge.org
We conducted a comparative retrospective study to quantify the impact of coronavirus
disease 2019 (COVID-19) on patient safety. We found a statistically significant increase in …

Improving antimicrobial use through better diagnosis: the relationship between diagnostic stewardship and antimicrobial stewardship

TSN Ku, M Al Mohajer, JA Newton… - Infection Control & …, 2023 - cambridge.org
Antimicrobial stewardship programs (ASPs) exist to optimize antibiotic use, reduce selection
for antimicrobial-resistant microorganisms, and improve patient outcomes. Rapid and …

[HTML][HTML] Diagnostic stewardship for blood cultures in the emergency department: a multicenter validation and prospective evaluation of a machine learning prediction …

M Schinkel, AW Boerman, FC Bennis… - …, 2022 - thelancet.com
Background Overuse of blood cultures (BCs) in emergency departments (EDs) leads to low
yields and high numbers of contaminated cultures, accompanied by increased diagnostics …