Barrett's esophagus is an intestine-like metaplasia and precursor of esophageal
adenocarcinoma. Triggered by gastroesophageal reflux disease, the origin of this …

Context.—Barrett esophagus is a metaplastic, premalignant lesion associated with
approximately 0.5% annual incidence of progression to esophageal adenocarcinoma …

Background Barrett's esophagus (BE) is a premalignant condition caused by chronic
gastroesophageal reflux. BE patients have an increased risk of developing esophageal …

Background Gastroesophageal reflux disease (GERD), a disorder resulting from the
retrograde flow of gastric contents into the esophagus, affects an estimated 10–30% of the …

Background A human model of gastroesophageal reflux disease was used to examine the
contribution of a non-specialized columnar type of metaplasia (NSCM) and key molecular …

Gastroesophageal reflux disease (GERD) significantly impacts patient quality of life and is a
major risk factor for the development of Barrett's esophagus (BE) and esophageal …

Purpose As the premalignant lesion of human esophageal adenocarcinoma (EAC), Barrett's
esophagus (BE) is characterized by intestinal metaplasia in the normal esophagus (NE) …

Background Barrett's esophagus (BE) is a metaplastic precursor lesion of esophageal
adenocarcinoma (EA), the most rapidly increasing cancer in western societies. While the …

Objectives/Hypothesis Gastroesophageal reflux disease and associated metaplasia of the
esophagus (Barrett's esophagus [BE]) are primary risk factors for esophageal …

Barrett's esophagus (BE) is an acquired condition in which the normal lining of the
esophagus is replaced by intestinal metaplastic epithelium. BE can evolve to esophageal …