The role of mast cells, traditionally recognized for their involvement in immediate
hypersensitivity reactions, has garnered significant attention in liver diseases. Studies have …

Abstract Purpose of Review Provide an overview of the expanding landscape of mast cell
(MC)–targeting treatments in mast cell activation syndromes (MCAS). Recent Findings …

This study delves into the critical role of alarmins in chronic spontaneous urticaria (CSU),
focusing on their impact on disease severity and the quality of life (QoL) of patients. We …

Mastocytosis is a heterogeneous disease characterized by the expansion and accumulation
of neoplastic mast cells in various tissues. Diffuse cutaneous mastocytosis (DCM) is a rare …

Mast cells are tissue-resident immune cells strategically located in different compartments of
the normal human heart (the myocardium, pericardium, aortic valve, and close to nerves) as …

The pathophysiology of mast cell (MC)-driven disorders is diverse, ranging from localized
reactions to systemic disorders caused by abnormal accumulation and activation in multi …

Chronic urticaria (CU) is a mast cells (MC)-driven disease characterized by the development
of itching wheals and/or angioedema. In the last decades, outstanding progress has been …

Helicobacter pylori, a widely renowned bacterium, has recently gained attention owing to its
potential impact on extragastric health. The emergence of research linking H. pylori infection …

Chronic spontaneous urticaria (CSU) is a typical example of an intractable skin dis-ease
with no clear cause and significantly affects daily life of patients. Because CSU is a human …

Mastzellen (MZ) sind gewebeständige Effektorzellen des angeborenen und adaptiven
Immunsystems und wichtige Treiber von Entzündungsreaktionen. Aus evolutionärer Sicht …