ABSTRACT Elabela (ELA), Apela or Toddler peptide is a hormone peptide belonging to the
adipokine group and a component of apelinergic system, discovered in 2013-2014. Given its …

Adipose tissue is actually regarded as an endocrine organ, rather than as an organ that
merely stores energy. During the COVID-19 pandemic, obesity has undoubtedly emerged as …

Adipokines are peptide hormones produced by the adipose tissue involved in several
biological functions. Among adipokines, adiponectin (ADPN) has antidiabetic and anti …

Apelin is a key hormone in cardiovascular homeostasis that activates the apelin receptor
(APLNR), which is regarded as a promising therapeutic target for cardiovascular disease …

Heart failure (HF) remains a major medical and social problem. The NT-pro-brain natriuretic
peptide (NT-proBNP) and its active form, brain-type natriuretic peptide (BNP), in a simple …

Among the side effects of diabetes mellitus is diabetic nephropathy, the main reason for end-
stage kidney disease linked to increased mortality and morbidity. Early diagnostic …

Background and aim: Hypertension is a leading global burden of deaths, coronary heart
diseases, and stroke. Hypertension causes low-grade chronic systemic inflammation …

Apelin 是一种多功能生物活性肽, 通过与其受体APJ 结合发挥相应生物学效应. Apelin/APJ
系统作为机体重要调节者, 广泛参与心血管系统, 代谢系统, 神经系统等方面的生理和病理过程 …

Objective: This study aimed to investigate the effects of serum levels of apelin and CD40L on
major adverse cardiovascular events (MACEs) after percutaneous coronary intervention …

Biological markers have been thoroughly incorporated into clinical practice as a convenient
and simple method for diagnosing and monitoring the condition of patients. The analysis of …