Twin studies to GWAS: there and back again

NP Friedman, MT Banich, MC Keller - Trends in cognitive sciences, 2021 - cell.com
The field of human behavioral genetics has come full circle. It began by using twin/family
studies to estimate the relative importance of genetic and environmental influences. As large …

Behavioural genetics methods

EA Willoughby, TJC Polderman… - Nature Reviews Methods …, 2023 - nature.com
The question of why people show individual differences in their behaviours and capacities
has intrigued researchers for centuries. Behaviour genetics offers us various methods to …

Association of local variation in neighborhood disadvantage in metropolitan areas with youth neurocognition and brain structure

DA Hackman, D Cserbik, JC Chen, K Berhane… - Jama …, 2021 - jamanetwork.com
Importance Neighborhood disadvantage is an important social determinant of health in
childhood and adolescence. Less is known about the association of neighborhood …

Cultural evolution of genetic heritability

R Uchiyama, R Spicer… - Behavioral and Brain …, 2022 - cambridge.org
Behavioral genetics and cultural evolution have both revolutionized our understanding of
human behavior–largely independent of each other. Here, we reconcile these two fields …

Challenging the utility of polygenic scores for social science: Environmental confounding, downward causation, and unknown biology

CH Burt - Behavioral and brain sciences, 2023 - cambridge.org
The sociogenomics revolution is upon us, we are told. Whether revolutionary or not,
sociogenomics is poised to flourish given the ease of incorporating polygenic scores (or …

[PDF][PDF] Addressing the challenges of polygenic scores in human genetic research

J Novembre, C Stein, S Asgari… - The American Journal of …, 2022 - cell.com
The genotyping of millions of human samples has made it possible to evaluate variants
across the human genome for their possible association with risks for numerous diseases …

Examining the shared etiology of psychopathology with genome-wide association studies

TT Mallard, AD Grotzinger… - Physiological …, 2023 - journals.physiology.org
Genome-wide association studies (GWASs) have ushered in a new era of reproducible
discovery in psychiatric genetics. The field has now identified hundreds of common genetic …

The “Golden Age” of behavior genetics?

E Charney - Perspectives on Psychological Science, 2022 - journals.sagepub.com
The search for genetic risk factors underlying the presumed heritability of all human
behavior has unfolded in two phases. The first phase, characterized by candidate-gene …

[HTML][HTML] Overcoming attenuation bias in regressions using polygenic indices

H van Kippersluis, P Biroli, R Dias Pereira… - Nature …, 2023 - nature.com
Measurement error in polygenic indices (PGIs) attenuates the estimation of their effects in
regression models. We analyze and compare two approaches addressing this attenuation …

[HTML][HTML] Behaviour genetics and sleep: A narrative review of the last decade of quantitative and molecular genetic research in humans

JJ Madrid-Valero, AM Gregory - Sleep Medicine Reviews, 2023 - Elsevier
During the last decade quantitative and molecular genetic research on sleep has increased
considerably. New behavioural genetics techniques have marked a new era for sleep …