Therapeutic potential of honey and propolis on ocular disease

N Abd Rashid, SNF Mohammed, SA Syed Abd Halim… - Pharmaceuticals, 2022 - mdpi.com
Honey and propolis have recently become the key target of attention for treating certain
diseases and promoting overall health and well-being. A high content of flavonoids and …

Hepatoprotective effects of natural drugs: Current trends, scope, relevance and future perspectives

S Datta, D Aggarwal, N Sehrawat, M Yadav, V Sharma… - Phytomedicine, 2023 - Elsevier
Background: The liver is a well-known player in the metabolism and removal of drugs. Drug
metabolizing enzymes in the liver detoxify drugs and xenobiotics, ultimately leading to the …

A comparison of XGBoost, random forest, and nomograph for the prediction of disease severity in patients with COVID-19 pneumonia: implications of cytokine and …

W Hong, X Zhou, S Jin, Y Lu, J Pan, Q Lin… - Frontiers in Cellular …, 2022 - frontiersin.org
Background and Aims The aim of this study was to apply machine learning models and a
nomogram to differentiate critically ill from non-critically ill COVID-19 pneumonia patients …

Icariin exhibits protective effects on cisplatin-induced cardiotoxicity via ROS-mediated oxidative stress injury in vivo and in vitro

J Xia, J Hu, R Zhang, W Liu, H Zhang, Z Wang, S Jiang… - Phytomedicine, 2022 - Elsevier
Background Cisplatin-induced cardiotoxicity severely limits its clinical application as an
antitumor drug and increases the risk of cardiovascular disease. Icariin (ICA), the main …

Combination therapy as a promising way to fight oral cancer

JPN Silva, B Pinto, L Monteiro, PMA Silva, H Bousbaa - Pharmaceutics, 2023 - mdpi.com
Oral cancer is a highly aggressive tumor with invasive properties that can lead to metastasis
and high mortality rates. Conventional treatment strategies, such as surgery, chemotherapy …

Repurposing FDA-approved drugs against the toxicity of platinum-based anticancer drugs

AC Famurewa, AG Mukherjee, UR Wanjari, A Sukumar… - Life Sciences, 2022 - Elsevier
Platinum-based anticancer drugs (PADs), mainly cisplatin, carboplatin, and oxaliplatin, are
widely used efficacious long-standing anticancer agents for treating several cancer types …

Methanolic Phoenix dactylifera L. Extract Ameliorates Cisplatin-Induced Hepatic Injury in Male Rats

HN Gad El-Hak, HS Mahmoud, EA Ahmed… - Nutrients, 2022 - mdpi.com
This study investigated the ameliorative potential of methanolic date flesh extract (MDFE)
against cisplatin-induced hepatic injury. Twenty male rats (weighing 180–200 g) were …

Metabolic Profiling, Chemical Composition, Antioxidant Capacity, and In Vivo Hepato- and Nephroprotective Effects of Sonchus cornutus in Mice Exposed to Cisplatin

SS Elhady, RFA Abdelhameed, ET Mehanna… - Antioxidants, 2022 - mdpi.com
Sonchus cornutus (Asteraceae) is a wild. edible plant that represents a plentiful source of
polyphenolic compounds. For the first time, the metabolic analysis profiling demonstrated …

Glycyrrhizin arginine salt protects against cisplation-induced acute liver injury by repressing BECN1-mediated ferroptosis

J Guo, J Yin, P Liu, X Zhang, J Wei, M Wang… - Frontiers in …, 2023 - frontiersin.org
The study aimed to investigate the protective effects and biological mechanisms of
glycyrrhizin arginine salt (Gly-Arg) against cisplatin (Cis)-induced liver injury. Our data …

Longevity Spinach (Gynura procumbens) Ameliorated Oxidative Stress and Inflammatory Mediators in Cisplatin‐Induced Organ Dysfunction in Rats: Comprehensive in vivo …

M Chandra Shill, HAS El‐Nashar… - Chemistry & …, 2024 - Wiley Online Library
This study focused to assess the efficacy of Gynura procumbens (GP) leaf extract against
cisplatin (CP)‐induced hepatorenal complications in Wister albino rats. Additionally, it aims …