[HTML][HTML] The role of cytokines and chemokines in severe acute respiratory syndrome coronavirus 2 infections

RJ Hsu, WC Yu, GR Peng, CH Ye, SY Hu… - Frontiers in …, 2022 - frontiersin.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in countless
infections and caused millions of deaths since its emergence in 2019. Coronavirus disease …

[HTML][HTML] COVID-19-related mortality risk in people with severe mental illness: a systematic and critical review

M De Hert, V Mazereel, M Stroobants… - Frontiers in …, 2022 - frontiersin.org
Background: Increasing clinical evidence suggests that people with severe mental illness
(SMI), including schizophrenia spectrum disorders, bipolar disorder (BD), and major …

[HTML][HTML] Pulmonary fibrosis as a result of acute lung inflammation: molecular mechanisms, relevant in vivo models, prognostic and therapeutic approaches

IA Savin, MA Zenkova, AV Sen'kova - International Journal of Molecular …, 2022 - mdpi.com
Pulmonary fibrosis is a chronic progressive lung disease that steadily leads to lung
architecture disruption and respiratory failure. The development of pulmonary fibrosis is …

[HTML][HTML] Mitochondrial dynamics in SARS-COV2 spike protein treated human microglia: implications for neuro-COVID

E Clough, J Inigo, D Chandra, L Chaves… - Journal of Neuroimmune …, 2021 - Springer
Emerging clinical data from the current COVID-19 pandemic suggests that~ 40% of COVID-
19 patients develop neurological symptoms attributed to viral encephalitis while in COVID …

[HTML][HTML] Qingwenzhike Prescription Alleviates Acute Lung Injury Induced by LPS via Inhibiting TLR4/NF-kB Pathway and NLRP3 Inflammasome Activation

C Zhang, X Wang, C Wang, C He, Q Ma, J Li… - Frontiers in …, 2021 - frontiersin.org
Background: Acute lung injury (ALI) is characterized by dysfunction of the alveolar epithelial
membrane caused by acute inflammation and tissue injury. Qingwenzhike (QWZK) …

[HTML][HTML] From infection to immunity: understanding the response to SARS-CoV2 through in-silico modeling

F Castiglione, D Deb, AP Srivastava, P Liò… - Frontiers in …, 2021 - frontiersin.org
Background Immune system conditions of the patient is a key factor in COVID-19 infection
survival. A growing number of studies have focused on immunological determinants to …

[HTML][HTML] Dynamics of inflammatory markers in predicting mortality in COVID-19

A Parimoo, A Biswas, U Baitha, G Gupta, S Pandey… - Cureus, 2021 - ncbi.nlm.nih.gov
Methods We conducted a retrospective study of 142 patients admitted with COVID-19 in the
Department of Medicine at All India Institute of Medical Sciences, New Delhi, from May 2021 …

[HTML][HTML] Role of innate and adaptive cytokines in the survival of COVID-19 patients

J Monserrat, A Gómez-Lahoz, MA Ortega… - International journal of …, 2022 - mdpi.com
SARS-CoV-2 is a new coronavirus characterized by a high infection and transmission
capacity. A significant number of patients develop inadequate immune responses that …

Extensive Study on Hematological, Immunological, Inflammatory Markers, and Biochemical Profile to Identify the Risk Factors in COVID‐19 Patients

ET Ali, A Sajid Jabbar, HS Al Ali… - International Journal …, 2022 - Wiley Online Library
Background. Tissue damage caused by COVID‐19 could be detected by several clinical
indicators including hematological, immunological, biochemical, and inflammatory markers …

[HTML][HTML] Drug repurposing for COVID-19 based on an integrative meta-analysis of SARS-CoV-2 induced gene signature in human airway epithelium

RK Gupta, EL Nwachuku, BE Zusman, RM Jha… - Plos one, 2021 - journals.plos.org
Drug repurposing has the potential to bring existing de-risked drugs for effective intervention
in an ongoing pandemic—COVID-19 that has infected over 131 million, with 2.8 million …