Abstract (163 words) Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
induces coronavirus-19 disease (COVID-19) and is a major health concern. Following two …

Inflammation is an essential component of several respiratory diseases, such as chronic
obstructive pulmonary disease (COPD), asthma and acute respiratory distress syndrome …

Background Post-acute COVID-19 syndrome (PACS) is an emerging healthcare burden.
The risk factors associated with PACS remain largely unclear. The aim of this study was to …

Innate immune interferons (IFNs), including type I and III IFNs, constitute critical antiviral
mechanisms. Recent studies reveal that IFN dysregulation is key to determine COVID-19 …

Cause and mechanisms of persistent dyspnoea after recovery from COVID-19 are not well
described. The objective is to describe causal factors for persistent dyspnoea in patients …

Transfer of convalescent plasma (CP) had been proposed early during the SARS-CoV-2
pandemic as an accessible therapy, yet trial results worldwide have been mixed, potentially …

COVID‐19 is a complex disease, and many difficulties are faced today especially in the
proper choice of pharmacological treatments. The role of antiviral agents for COVID‐19 is …

Purpose It is critical to identify putative causal targets for SARS coronavirus 2, which may
guide drug repurposing options to reduce the public health burden of COVID-19. Methods …

Obesity prevails worldwide to an increasing effect. For example, up to 42% of American
adults are considered obese. Obese individuals are prone to a variety of complications of …

Although our current knowledge of the pathophysiology of COVID-19 is still fragmentary, the
information so far accrued on the tropism and life cycle of its etiological agent SARS-CoV-2 …