COVID-19 at a glance: An up-to-date overview on variants, drug design and therapies

D Iacopetta, J Ceramella, A Catalano, C Saturnino… - Viruses, 2022 - mdpi.com
Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is a member of the
Coronavirus family which caused the worldwide pandemic of human respiratory illness …

COVID-19 vaccines uptake: Public knowledge, awareness, perception and acceptance among adult Africans

JK Ahiakpa, NT Cosmas, FE Anyiam, KO Enalume… - PLoS …, 2022 - journals.plos.org
Introduction The willingness of Africa's population to patronise the COVID-19 vaccines is
critical to the efficiency of national immunisation programmes. This study surveys the views …

Targeting the pentose phosphate pathway for SARS-CoV-2 therapy

D Bojkova, R Costa, P Reus, M Bechtel, MC Jaboreck… - Metabolites, 2021 - mdpi.com
SARS-CoV-2 is causing the coronavirus disease 2019 (COVID-19) pandemic, for which
effective pharmacological therapies are needed. SARS-CoV-2 induces a shift of the host cell …

Heterocyclic compounds as antiviral drugs: Synthesis, structure–activity relationship and traditional applications

GC dos Santos, LM Martins… - Journal of …, 2021 - Wiley Online Library
A virus outbreak challenges the economic, medical, and public health infrastructure
worldwide. More than one virus capable of triggering diseases have been identified per year …

Who Gets Sick From COVID-19? Sociodemographic Correlates of Severe Adult Health Outcomes During Alpha-and Delta-Variant Predominant Periods: September …

SC Wei, D Freeman, A Himschoot… - The Journal of …, 2024 - academic.oup.com
Background Because COVID-19 case data do not capture most SARS-CoV-2 infections, the
actual risk of severe disease and death per infection is unknown. Integrating …

SARS-CoV-2 receptor binding domain fusion protein efficiently neutralizes virus infection

AE Chaouat, H Achdout, I Kol, O Berhani, G Roi… - PLoS …, 2021 - journals.plos.org
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is responsible for the
COVID-19 pandemic. Currently, as dangerous mutations emerge, there is an increased …

Bacterial co-infections and antimicrobial resistance in patients hospitalized with suspected or confirmed COVID-19 pneumonia in Kazakhstan

A Lavrinenko, S Kolesnichenko, I Kadyrova… - Pathogens, 2023 - mdpi.com
Our study was carried out to characterize respiratory tract microbiota in patients with “COVID-
like pneumonia” in Kazakhstan and analyze differences between COVID-19 positive and …

A potential role of the CD47/SIRPalpha axis in COVID-19 pathogenesis

KM McLaughlin, D Bojkova, JD Kandler… - Current issues in …, 2021 - mdpi.com
The coronavirus SARS-CoV-2 is the cause of the ongoing COVID-19 pandemic. Most SARS-
CoV-2 infections are mild or even asymptomatic. However, a small fraction of infected …

Old drugs, new tricks: leveraging known compounds to disrupt coronavirus-induced cytokine storm

S Richman, C Lyman, A Nesterova, A Yuryev… - NPJ Systems Biology …, 2022 - nature.com
A major complication in COVID-19 infection consists in the onset of acute respiratory distress
fueled by a dysregulation of the host immune network that leads to a run-away cytokine …

Phase II clinical trial of combination therapy with favipiravir and methylprednisolone for COVID-19 with non-critical respiratory failure

Y Shindo, Y Kondoh, A Kada, Y Doi, K Tomii… - Infectious Diseases and …, 2021 - Springer
Introduction The administration of systemic corticosteroids is a key strategy for improving
COVID-19 outcomes. However, evidence is lacking on combination therapies of antiviral …