Infectious diseases have the ability to impact health on a global scale, as is being
demonstrated by the current coronavirus disease 2019 (COVID-19) pandemic. The …

Vaccination is still the most efficient way to prevent an infection with influenza viruses.
Nevertheless, existing commercial vaccines face serious limitations such as availability …

The Zika virus (ZIKV) epidemic poses a substantial threat to the public, and the development
of safe and effective vaccines is a demanding challenge. In this study, we constructed a kind …

The nasal priming with Lactobacillus rhamnosus CRL1505 modulates the respiratory
antiviral innate immune response and improves protection against influenza virus (IFV) …

Traditional influenza vaccines generate strain-specific antibodies which cannot provide
protection against divergent influenza virus strains. Further, due to frequent antigenic shifts …

It is of international priority to develop a vaccine against sexually transmitted Chlamydia
trachomatis infections to combat the continued global spread of the infection. The optimal …

Abstract Background In England, the Joint Committee for Vaccination and Immunisation
recommended a spring 2023 booster programme for all adults aged 75 years and older and …

Combined cellular and humoral host immune response determine the clinical course of a
viral infection and effectiveness of vaccination, but currently the cellular immune response …

Annual vaccination is the best prevention of influenza. However, the immunogenicity of
influenza vaccines varies among different populations. It is important to fully identify the …

Antigen sparing is an important strategy for pandemic vaccine development because of the
limitation of worldwide vaccine production during disease outbreaks. However, several …