Factors influencing the immunogenicity of influenza vaccines

S Wen, Z Wu, S Zhong, M Li, Y Shu - Human vaccines & …, 2021 - Taylor & Francis
Annual vaccination is the best prevention of influenza. However, the immunogenicity of
influenza vaccines varies among different populations. It is important to fully identify the …

Nanotherapeutic systems for delivering cancer vaccines: recent advances

S Beg, KS Alharbi, NK Alruwaili, NH Alotaibi… - …, 2020 - Taylor & Francis
With an increase in the global burden of cancer-related deaths, the quest for developing
new therapeutic solutions has taken momentum. In this regard, the idea of using cancer …

14-Deoxy-11, 12-didehydroandrographolide inhibits apoptosis in influenza A (H5N1) virus-infected human lung epithelial cells via the caspase-9-dependent intrinsic …

W Cai, H Wen, Q Zhou, L Wu, Y Chen, H Zhou, M Jin - Antiviral Research, 2020 - Elsevier
Influenza A virus (IAV) infection represents a global health challenge. Excavating antiviral
active components from traditional Chinese medicine (TCM) is a promising anti-IAV strategy …

Validation of multi-epitope peptides encapsulated in PLGA nanoparticles against influenza A virus

WT Heng, HX Lim, KO Tan, CL Poh - Pharmaceutical Research, 2023 - Springer
Background Influenza is a highly contagious respiratory disease which poses a serious
threat to public health globally, causing severe diseases in 3-5 million humans and resulting …

A review on equine influenza from a human influenza perspective

F Whitlock, PR Murcia, JR Newton - Viruses, 2022 - mdpi.com
Influenza A viruses (IAVs) have a main natural reservoir in wild birds. IAVs are highly
contagious, continually evolve, and have a wide host range that includes various …

Adjuvantation of influenza vaccines to induce cross-protective immunity

Z Li, Y Zhao, Y Li, X Chen - Vaccines, 2021 - mdpi.com
Influenza poses a huge threat to global public health. Influenza vaccines are the most
effective and cost-effective means to control influenza. Current influenza vaccines mainly …

Combination of STING pathway agonist with saponin is an effective adjuvant in immunosenescent mice

EV Vassilieva, DW Taylor, RW Compans - Frontiers in Immunology, 2019 - frontiersin.org
There is an urgent need to improve protective responses to influenza vaccination in the
elderly population, which is at especially high risk for adverse outcomes from influenza …

Effectiveness of the Sanofi/GSK (VidPrevtyn Beta) and Pfizer-BioNTech (Comirnaty Original/Omicron BA. 4-5) bivalent vaccines against hospitalisation in England

FCM Kirsebom, N Andrews, J Stowe, G Dabrera… - …, 2024 - thelancet.com
Summary Background The Sanofi/GSK AS03-adjuvanted (VidPrevtyn Beta) vaccine and the
Pfizer-BioNTech mRNA (Comirnaty Original/Omicron BA. 4-5) bivalent vaccine were offered …

Next-generation influenza HA immunogens and adjuvants in pursuit of a broadly protective vaccine

KA Nagashima, JJ Mousa - Viruses, 2021 - mdpi.com
Influenza virus, a highly mutable respiratory pathogen, causes significant disease nearly
every year. Current vaccines are designed to protect against circulating influenza strains of a …

Quillaja brasiliensis nanoparticle adjuvant formulation improves the efficacy of an inactivated trivalent influenza vaccine in mice

F Silveira, M Rivera-Patron, N Deshpande… - Frontiers in …, 2023 - frontiersin.org
The threat of viral influenza infections has sparked research efforts to develop vaccines that
can induce broadly protective immunity with safe adjuvants that trigger robust immune …