Pulmonary fibrosis in COVID‐19 survivors: Predictive factors and risk reduction strategies

AS Ojo, SA Balogun, OT Williams… - Pulmonary medicine, 2020 - Wiley Online Library
Although pulmonary fibrosis can occur in the absence of a clear‐cut inciting agent, and
without a clinically clear initial acute inflammatory phase, it is more commonly associated …

Post-COVID-19 pulmonary fibrosis: novel sequelae of the current pandemic

SR Ambardar, SL Hightower, NA Huprikar… - Journal of clinical …, 2021 - mdpi.com
Since the initial identification of the novel coronavirus SARS-CoV-2 in December 2019, the
COVID-19 pandemic has become a leading cause of morbidity and mortality worldwide. As …

[HTML][HTML] Post-COVID lung fibrosis: The tsunami that will follow the earthquake

ZF Udwadia, PA Koul, L Richeldi - Lung India, 2021 - journals.lww.com
The SARS-CoV-2 pandemic has already infected in excess of 50 million people worldwide
and resulted in 1.2 million deaths. While the majority of those infected will not have long …

From the radiologic pathology archives: organization and fibrosis as a response to lung injury in diffuse alveolar damage, organizing pneumonia, and acute fibrinous …

SJ Kligerman, TJ Franks, JR Galvin - Radiographics, 2013 - pubs.rsna.org
Organization, characterized by fibroblast proliferation, is a common and nearly universal
response to lung injury whether it is focal or diffuse. Despite the vast range of injurious …

Nanoparticle-induced pulmonary toxicity

JJ Li, S Muralikrishnan, CT Ng… - Experimental biology …, 2010 - journals.sagepub.com
In recent decades, advances in nanotechnology engineering have given rise to the rapid
development of many novel applications in the biomedical field. However, studies into the …

New mechanisms of pulmonary fibrosis

RM Strieter, B Mehrad - Chest, 2009 - Elsevier
The understanding of the pathogenesis of pulmonary fibrosis continues to evolve. The initial
hypothetical model suggested chronic inflammation as the cause of pulmonary fibrosis …

Respiratory epithelial cells in innate immunity to influenza virus infection

CJ Sanders, PC Doherty, PG Thomas - Cell and tissue research, 2011 - Springer
Infection by influenza virus leads to respiratory failure characterized by acute lung injury
associated with alveolar edema, necrotizing bronchiolitis, and excessive bleeding. Severe …

The pathogenesis, epidemiology and biomarkers of susceptibility of pulmonary fibrosis in COVID-19 survivors

A Vianello, G Guarnieri, F Braccioni… - Clinical Chemistry and …, 2022 - degruyter.com
Pulmonary fibrosis (PF), a pathological outcome of chronic and acute interstitial lung
diseases associated to compromised wound healing, is a key component of the “post-acute …

Macrophage heterogeneity in respiratory diseases

CE Boorsma, C Draijer, BN Melgert - Mediators of inflammation, 2013 - Wiley Online Library
Macrophages are among the most abundant cells in the respiratory tract, and they can have
strikingly different phenotypes within this environment. Our knowledge of the different …

cAMP and Epac in the regulation of tissue fibrosis

PA Insel, F Murray, U Yokoyama… - British journal of …, 2012 - Wiley Online Library
Fibrosis, the result of excess deposition of extracellular matrix (ECM), in particular collagen,
leads to scarring and loss of function in tissues that include the heart, lung, kidney and liver …