Vaccine technologies and platforms for infectious diseases: Current progress, challenges, and opportunities

M Ghattas, G Dwivedi, M Lavertu, MG Alameh - Vaccines, 2021 - mdpi.com
Vaccination is a key component of public health policy with demonstrated cost-effective
benefits in protecting both human and animal populations. Vaccines can be manufactured …

Nano-bio interactions in mRNA nanomedicine: Challenges and opportunities for targeted mRNA delivery

Q Saiding, Z Zhang, S Chen, F Xiao, Y Chen… - Advanced Drug Delivery …, 2023 - Elsevier
Upon entering the biological milieu, nanomedicines swiftly interact with the surrounding
tissue fluid, subsequently being enveloped by a dynamic interplay of biomacromolecules …

Virus-like particles: fundamentals and biomedical applications

JL Mejía-Méndez, R Vazquez-Duhalt… - International journal of …, 2022 - mdpi.com
Nanotechnology is a fast-evolving field focused on fabricating nanoscale objects for
industrial, cosmetic, and therapeutic applications. Virus-like particles (VLPs) are self …

Applications of synthetic biology in medical and pharmaceutical fields

X Yan, X Liu, C Zhao, GQ Chen - Signal transduction and targeted …, 2023 - nature.com
Synthetic biology aims to design or assemble existing bioparts or bio-components for useful
bioproperties. During the past decades, progresses have been made to build delicate …

Virus-like particles as nanocarriers for intracellular delivery of biomolecules and compounds

J He, L Yu, X Lin, X Liu, Y Zhang, F Yang, W Deng - Viruses, 2022 - mdpi.com
Virus-like particles (VLPs) are nanostructures assemble from viral proteins. Besides widely
used for vaccine development, VLPs have also been explored as nanocarriers for cargo …

Virus‐like particles as powerful vaccination strategy against human viruses

I Hadj Hassine, M Ben M'hadheb… - Reviews in Medical …, 2024 - Wiley Online Library
Nowadays, viruses are not only seen as causative agents of viral infectious diseases but
also as valuable research materials for various biomedical purposes, including recombinant …

Virus-like particles as an instrument of vaccine production

BV Syomin, YV Ilyin - Molecular biology, 2019 - Springer
The paper discusses the techniques which are currently implemented for vaccine production
based on virus-like particles (VLPs). The factors which determine the characteristics of VLP …

Advances and challenges in cell-free incorporation of unnatural amino acids into proteins

W Gao, E Cho, Y Liu, Y Lu - Frontiers in pharmacology, 2019 - frontiersin.org
Incorporation of unnatural amino acids (UNAAs) into proteins currently is an active biological
research area for various fundamental and applied science. In this context, cell-free …

Biomimetic nanoparticles for DC vaccination: a versatile approach to boost cancer immunotherapy

L Meng, Z Teng, S Yang, N Wang, YH Guan, X Chen… - Nanoscale, 2023 - pubs.rsc.org
Cancer immunotherapy, which harnesses the immune system to fight cancer, has begun to
make a breakthrough in clinical applications. Dendritic cells (DCs) are the bridge linking …

The pharmacology of plant virus nanoparticles

CI Nkanga, NF Steinmetz - Virology, 2021 - Elsevier
The application of nanoparticles for medical purposes has made enormous strides in
providing new solutions to health problems. The observation that plant virus-based …