[HTML][HTML] Training and deploying a deep learning model for endoscopic severity grading in ulcerative colitis using multicenter clinical trial data

BG Becker, F Arcadu, A Thalhammer… - Therapeutic …, 2021 - ncbi.nlm.nih.gov
Methods: Here we propose an end-to-end fully automated system based on deep learning to
predict a binary version of the Mayo Clinic Endoscopic Subscore directly from raw …

Defining endoscopic response and remission in ulcerative colitis clinical trials: an international consensus

L Vuitton, L Peyrin‐Biroulet… - Alimentary …, 2017 - Wiley Online Library
Background Recently, endpoints for clinical trials have been changing from measuring
clinical response to mucosal healing in ulcerative colitis. Endoscopic evaluation is the …

The Modified Mayo Endoscopic Score (MMES): a new index for the assessment of extension and severity of endoscopic activity in ulcerative colitis patients

T Lobatón, T Bessissow, G De Hertogh… - Journal of Crohn's …, 2015 - academic.oup.com
Background and aims: Current endoscopic activity scores for ulcerative colitis (UC) do not
take into account the extent of mucosal inflammation. We have developed a simple …

Endoscopy in pediatric inflammatory bowel disease: a position paper on behalf of the Porto IBD Group of the European Society for Pediatric Gastroenterology …

S Oliva, M Thomson, L De Ridder… - Journal of pediatric …, 2018 - journals.lww.com
Endoscopy is a central tool for the evaluation and management of inflammatory bowel
disease (IBD). In the last few decades, gastrointestinal (GI) endoscopy has undergone …

A review of the therapeutic management of ulcerative colitis

N Aslam, SW Lo, R Sikafi, T Barnes… - Therapeutic …, 2022 - journals.sagepub.com
Ulcerative colitis (UC) is a chronic relapsing and remitting gastrointestinal disorder of
uncertain aetiology. The last two decades have seen an expansion in the therapeutic …

[HTML][HTML] Definition and evaluation of mucosal healing in clinical practice

S Mazzuoli, FW Guglielmi, E Antonelli… - Digestive and Liver …, 2013 - Elsevier
Since the introduction of biological therapy, endoscopic and histological remission, ie
mucosal healing, has become an important therapeutic goal in Crohn's Disease and …

Histological remission in ulcerative colitis: under the microscope is the cure

T Chateau, R Feakins… - Official journal of the …, 2020 - journals.lww.com
In recent years, the therapeutic goals in ulcerative colitis (UC) have become increasingly
stringent. Histological features seem to be a reliable predictor of disease outcomes after …

Endoscopic evaluation of surgically altered bowel in inflammatory bowel disease: a consensus guideline from the Global Interventional Inflammatory Bowel Disease …

B Shen, GS Kochhar, U Navaneethan… - The Lancet …, 2021 - thelancet.com
The majority of patients with Crohn's disease and a proportion of patients with ulcerative
colitis will ultimately require surgical treatment despite advances in diagnosis, therapy, and …

Different levels of healing in inflammatory bowel diseases: mucosal, histological, transmural, barrier and complete healing

MF Neurath, M Vieth - Gut, 2023 - gut.bmj.com
Mucosal healing on endoscopy has emerged as a key prognostic parameter in the
management of patients with IBD (Crohn's disease, ulcerative colitis/UC) and can predict …

Biochemical biomarkers of mucosal healing for inflammatory bowel disease in adults

M Krzystek-Korpacka, R Kempiński, M Bromke… - Diagnostics, 2020 - mdpi.com
Mucosal healing (MH) is the key therapeutic target of inflammatory bowel disease (IBD). The
evaluation of MH remains challenging, with endoscopy being the golden standard. We …