[HTML][HTML] Inflammatory indexes for assessing the severity and disease progression of ulcerative colitis: a single-center retrospective study

H Lin, Z Bai, Q Wu, G Chu, Y Zhang, X Guo… - Frontiers in Public …, 2022 - frontiersin.org
Background Active and severe ulcerative colitis (UC) and non-response to 5-aminosalicylic
acid (5-ASA) are related to poor outcomes and should be accurately identified. Several …

[HTML][HTML] A review of colonoscopy in intestinal diseases

SM Hong, DH Baek - Diagnostics, 2023 - mdpi.com
Since the development of the fiberoptic colonoscope in the late 1960s, colonoscopy has
been a useful tool to diagnose and treat various intestinal diseases. This article reviews the …

Development and reliability of the new endoscopic virtual chromoendoscopy score: the PICaSSO (Paddington International Virtual ChromoendoScopy ScOre) in …

M Iacucci, M Daperno, M Lazarev, R Arsenascu… - Gastrointestinal …, 2017 - Elsevier
Background and Aims Endoscopic inflammation and healing are important therapeutic
endpoints in ulcerative colitis (UC). We developed and validated a new electronic virtual …

Assessment of mucosal healing in inflammatory bowel disease

PS Dulai, BG Levesque, BG Feagan, G D'Haens… - Gastrointestinal …, 2015 - Elsevier
Background and Aims Mucosal healing is an important treatment end-point in inflammatory
bowel disease, and achieving mucosal healing has been demonstrated to improve disease …

Mucosal healing in ulcerative colitis–when zero is better

P Boal Carvalho, F Dias de Castro… - Journal of Crohn's …, 2016 - academic.oup.com
Background and aims: Extensive evidence has underlined the importance of mucosal
healing as a treatment aim for ulcerative colitis (UC). We aimed to assess differences in the …

Training and deploying a deep learning model for endoscopic severity grading in ulcerative colitis using multicenter clinical trial data

B Gutierrez Becker, F Arcadu… - Therapeutic …, 2021 - journals.sagepub.com
Introduction: The Mayo Clinic Endoscopic Subscore is a commonly used grading system to
assess the severity of ulcerative colitis. Correctly grading colonoscopies using the Mayo …

[HTML][HTML] Assessment of disease activity in inflammatory bowel diseases: non-invasive biomarkers and endoscopic scores

BL Rodrigues, MC Mazzaro, CK Nagasako… - World Journal of …, 2020 - ncbi.nlm.nih.gov
Inflammatory bowel diseases (IBD) comprise two major forms: Crohn's disease and
ulcerative colitis. The diagnosis of IBD is based on clinical symptoms combined with results …

[HTML][HTML] Using computer vision to improve endoscopic disease quantification in therapeutic clinical trials of ulcerative colitis

RW Stidham, L Cai, S Cheng, F Rajaei, T Hiatt… - Gastroenterology, 2024 - Elsevier
Background & Aims Endoscopic assessment of ulcerative colitis (UC) typically reports only
the maximum severity observed. Computer vision methods may better quantify mucosal …

A systematic review of the measurement of endoscopic healing in ulcerative colitis clinical trials: recommendations and implications for future research

MA Samaan, MH Mosli, WJ Sandborn… - Inflammatory bowel …, 2014 - academic.oup.com
Background Assessment of endoscopic disease activity, as measured by various
endoscopic evaluative instruments, is an essential part of quantifying disease activity in …

Designing clinical trials in paediatric inflammatory bowel diseases: a PIBDnet commentary

D Turner, AM Griffiths, D Wilson, DR Mould… - Gut, 2020 - gut.bmj.com
Introduction The optimal trial design for assessing novel therapies in paediatric IBD (PIBD) is
a subject of intense ongoing global discussions and debate among the different …