Oxidative stress, redox regulation and diseases of cellular differentiation

ZW Ye, J Zhang, DM Townsend, KD Tew - Biochimica et Biophysica Acta …, 2015 - Elsevier
Background Within cells, there is a narrow concentration threshold that governs whether
reactive oxygen species (ROS) induce toxicity or act as second messengers. Scope of …

Selenium and selenoproteins in adipose tissue physiology and obesity

AA Tinkov, OP Ajsuvakova, T Filippini, JC Zhou, XG Lei… - Biomolecules, 2020 - mdpi.com
Selenium (Se) homeostasis is tightly related to carbohydrate and lipid metabolism, but its
possible roles in obesity development and in adipocyte metabolism are unclear. The …

Serum miRNA signatures are indicative of skeletal fractures in postmenopausal women with and without type 2 diabetes and influence osteogenic and adipogenic …

U Heilmeier, M Hackl, S Skalicky… - Journal of Bone and …, 2016 - academic.oup.com
Standard DXA measurements, including Fracture Risk Assessment Tool (FRAX) scores,
have shown limitations in assessing fracture risk in Type 2 Diabetes (T2D), underscoring the …

Chronic stress, epigenetics, and adipose tissue metabolism in the obese state

Y Xiao, D Liu, MA Cline, ER Gilbert - Nutrition & metabolism, 2020 - Springer
In obesity, endocrine and metabolic perturbations, including those induced by chronic
activation of the hypothalamus–pituitary–adrenal axis, are associated with the accumulation …

MicroRNA 140 promotes expression of long noncoding RNA NEAT1 in adipogenesis

R Gernapudi, B Wolfson, Y Zhang, Y Yao… - … and cellular biology, 2016 - Am Soc Microbiol
More than 40% of the US population are clinically obese and suffer from metabolic
syndrome with an increased risk of postmenopausal estrogen receptor-positive breast …

Differential effects of dietary flavonoids on adipogenesis

M Khalilpourfarshbafi, K Gholami, DD Murugan… - European journal of …, 2019 - Springer
Propose Obesity is a fast growing epidemic worldwide. During obesity, the increase in
adipose tissue mass arise from two different mechanisms, namely, hyperplasia and …

A review on possible therapeutic targets to contain obesity: The role of phytochemicals

M Balaji, MS Ganjayi, GENH Kumar, BN Parim… - Obesity research & …, 2016 - Elsevier
The prevalence and severity of obesity has increased markedly in recent decades making it
a global public health concern. Since obesity is a potential risk factor in the development of …

The clinical potential of adipogenesis and obesity-related microRNAs

M Zaiou, H El Amri, A Bakillah - Nutrition, Metabolism and Cardiovascular …, 2018 - Elsevier
Obesity is a growing health problem commonly associated with numerous metabolic
disorders including type 2 diabetes, hypertension, cardiovascular disease, and some forms …

The mammalian “obesogen” tributyltin targets hepatic triglyceride accumulation and the transcriptional regulation of lipid metabolism in the liver and brain of zebrafish

A Lyssimachou, JG Santos, A André, J Soares, D Lima… - PloS one, 2015 - journals.plos.org
Recent findings indicate that different Endocrine Disrupting Chemicals (EDCs) interfere with
lipid metabolic pathways in mammals and promote fat accumulation, a previously unknown …

Elucidating the preadipocyte and its role in adipocyte formation: a comprehensive review

CN Sarantopoulos, DA Banyard, ME Ziegler… - Stem Cell Reviews and …, 2018 - Springer
Adipogenesis is a complex process whereby the multipotent adipose-derived stem cell is
converted to a preadipocyte before terminal differentiation into the mature adipocyte …