Metabolomics in diabetic retinopathy: from potential biomarkers to molecular basis of oxidative stress

Q Jian, Y Wu, F Zhang - Cells, 2022 - mdpi.com
Diabetic retinopathy (DR), the leading cause of blindness in working-age adults, is one of
the most common complications of diabetes mellitus (DM) featured by metabolic disorders …

Metabolomics of various samples advancing biomarker discovery and pathogenesis elucidation for diabetic retinopathy

X Du, L Yang, L Kong, Y Sun, K Shen, Y Cai… - Frontiers in …, 2022 - frontiersin.org
Diabetic retinopathy (DR) is a universal microvascular complication of diabetes mellitus
(DM), which is the main reason for global sight damage/loss in middle-aged and/or older …

Metabolites as risk factors for diabetic retinopathy in patients with type 2 diabetes: a 12-year follow-up study

L Fernandes Silva, J Hokkanen… - The Journal of …, 2024 - academic.oup.com
Context Diabetic retinopathy (DR) is a specific microvascular complication in patients with
diabetes and the leading cause of blindness. Recent advances in omics, especially …

Amino acids metabolism in retinopathy: from clinical and basic research perspective

M Xia, F Zhang - Metabolites, 2022 - mdpi.com
Retinopathy, including age-related macular degeneration (AMD), diabetic retinopathy (DR),
and retinopathy of prematurity (ROP), are the leading cause of blindness among seniors …

New insight of metabolomics in ocular diseases in the context of 3P medicine

Q Zhang, N Wang, Y Rui, Y Xia, S Xiong, X Xia - EPMA Journal, 2023 - Springer
Metabolomics refers to the high-through untargeted or targeted screening of metabolites in
biofluids, cells, and tissues. Metabolome reflects the functional states of cells and organs of …

[HTML][HTML] Neutrophils and neutrophil extracellular trap components: Emerging biomarkers and therapeutic targets for age-related eye diseases

I Martínez-Alberquilla, X Gasull, P Pérez-Luna… - Ageing Research …, 2022 - Elsevier
Age-related eye diseases, including dry eye, glaucoma, age-related macular degeneration,
and diabetic retinopathy, represent a major global health issue based on their increasing …

Research progress on the pathogenesis of diabetic retinopathy

H Li, X Liu, H Zhong, J Fang, X Li, R Shi, Q Yu - BMC ophthalmology, 2023 - Springer
Diabetic retinopathy is one of the most common and serious microvascular complications of
diabetes mellitus. There are many factors leading to diabetic retinopathy, and its …

Integrated metabolomics and transcriptomics reveal metabolic patterns in retina of STZ-induced diabetic retinopathy mouse model

R Wang, Q Jian, G Hu, R Du, X Xu, F Zhang - Metabolites, 2022 - mdpi.com
Diabetic retinopathy (DR), as the leading cause of vision loss in the working-age population,
exhibits unique metabolite profiles in human plasma and vitreous. However, those in retina …

Untargeted multiomics approach coupling lipidomics and metabolomics profiling reveals new insights in diabetic retinopathy

P Ancel, JC Martin, E Doukbi, M Houssays… - International Journal of …, 2023 - mdpi.com
Diabetic retinopathy (DR) is a microvascular complication of diabetes mellitus (DM) which is
the main cause of vision loss in the working-age population. Currently known risk factors …

Advances and Perspectives in Relation to the Molecular Basis of Diabetic Retinopathy—A Review

M Błaszkiewicz, A Walulik, K Florek, I Górecki… - Biomedicines, 2023 - mdpi.com
Diabetes mellitus (DM) is a growing problem nowadays, and diabetic retinopathy (DR) is its
predominant complication. Currently, DR diagnosis primarily relies on fundoscopic …