Introduction Chloroquine and hydroxychloroquine are widely used in the long-term
treatment of connective tissue disease and usually considered safe. However, chloroquine …

The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has affected millions of people worldwide, igniting …

Coronaviruses can cause respiratory and enteric disease in a wide variety of human and
animal hosts. The 2003 outbreak of severe acute respiratory syndrome (SARS) first …

Chloroquine (CQ) and hydroxychloroquine (HCQ) are well-known 4-aminoquinoline
antimalarial agents. Scientific evidence also supports the use of CQ and HCQ in the …

Chloroquine (CQ) and hydroxychloroquine (HCQ) are the most common drugs used to
relieve acute and chronic inflammatory diseases. In this article, we present a review about …

Highlights•Chloroquine is used for anti-malaria, anti-cancer and anti-virus treatment.•The
efficacy of hydroxychloroquine against COVID-19 is controversial.•Several quinoline …

No specific antivirals are currently available for two emerging infectious diseases, Middle
East respiratory syndrome (MERS) and severe acute respiratory syndrome (SARS). A …

A systematic screen of FDA-approved drugs was performed to identify compounds with in
vitro antiviral activities against Ebola virus (EBOV). Compounds active (> 50% viral inhibition …

Abstract The coronavirus disease (COVID-19) caused by the novel severe acute respiratory
syndrome coronavirus 2 (SARS-CoV-2) has now spread to> 200 countries posing a global …

Objective Antipsychotic effects of immunomodulating drugs have been suggested; however,
a thorough, comprehensive meta-analysis on the effect and safety of anti-inflammatory add …