Effect of genotype-guided oral P2Y12 inhibitor selection vs conventional clopidogrel therapy on ischemic outcomes after percutaneous coronary intervention: the …

NL Pereira, ME Farkouh, D So, R Lennon, N Geller… - Jama, 2020 - jamanetwork.com
Importance After percutaneous coronary intervention (PCI), patients withCYP2C19* 2or*
3loss-of-function (LOF) variants treated with clopidogrel have increased risk of ischemic …

Left atrial appendage occlusion during cardiac surgery to prevent stroke

RP Whitlock, EP Belley-Cote, D Paparella… - … England Journal of …, 2021 - Mass Medical Soc
Background Surgical occlusion of the left atrial appendage has been hypothesized to
prevent ischemic stroke in patients with atrial fibrillation, but this has not been proved. The …

Effect of ticagrelor monotherapy vs ticagrelor with aspirin on major bleeding and cardiovascular events in patients with acute coronary syndrome: the TICO …

BK Kim, SJ Hong, YH Cho, KH Yun, YH Kim, Y Suh… - Jama, 2020 - jamanetwork.com
Importance Discontinuing aspirin after short-term dual antiplatelet therapy (DAPT) was
evaluated as a bleeding reduction strategy. However, the strategy of ticagrelor monotherapy …

Therapeutic versus prophylactic anticoagulation for severe COVID-19: A randomized phase II clinical trial (HESACOVID)

ACB Lemos, DA do Espírito Santo, MC Salvetti… - Thrombosis research, 2020 - Elsevier
Abstract Introduction Coronavirus disease 2019 (COVID-19) causes a hypercoagulable
state. Several autopsy studies have found microthrombi in pulmonary circulation. Methods In …

Edoxaban-based versus vitamin K antagonist-based antithrombotic regimen after successful coronary stenting in patients with atrial fibrillation (ENTRUST-AF PCI): a …

P Vranckx, M Valgimigli, L Eckardt, J Tijssen… - The Lancet, 2019 - thelancet.com
Background We aimed to assess the safety of edoxaban in combination with P2Y12
inhibition in patients with atrial fibrillation who had percutaneous coronary intervention (PCI) …

Rivaroxaban in peripheral artery disease after revascularization

MP Bonaca, RM Bauersachs, SS Anand… - … England Journal of …, 2020 - Mass Medical Soc
Background Patients with peripheral artery disease who have undergone lower-extremity
revascularization are at high risk for major adverse limb and cardiovascular events. The …

P2Y12 inhibitor monotherapy or dual antiplatelet therapy after coronary revascularisation: individual patient level meta-analysis of randomised controlled trials

M Valgimigli, F Gragnano, M Branca, A Franzone… - Bmj, 2021 - bmj.com
Objective To assess the risks and benefits of P2Y 12 inhibitor monotherapy compared with
dual antiplatelet therapy (DAPT) and whether these associations are modified by patients' …

Effect of 1-month dual antiplatelet therapy followed by clopidogrel vs 12-month dual antiplatelet therapy on cardiovascular and bleeding events in patients receiving …

H Watanabe, T Domei, T Morimoto, M Natsuaki… - Jama, 2019 - jamanetwork.com
Importance Very short mandatory dual antiplatelet therapy (DAPT) after percutaneous
coronary intervention (PCI) with a drug-eluting stent may be an attractive option. Objective …

Venoarterial extracorporeal membrane oxygenation in patients with infarct-related cardiogenic shock: an individual patient data meta-analysis of randomised trials

U Zeymer, A Freund, M Hochadel, P Ostadal… - The Lancet, 2023 - thelancet.com
Background Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly
used in patients with cardiogenic shock despite the lack of evidence from adequately …

Heart failure in COVID‐19 patients: prevalence, incidence and prognostic implications

JR Rey, J Caro‐Codón, SO Rosillo… - European journal of …, 2020 - Wiley Online Library
Aims Data on the impact of COVID‐19 in chronic heart failure (CHF) patients and its
potential to trigger acute heart failure (AHF) are lacking. The aim of this work was to study …