Microfluidics: innovations in materials and their fabrication and functionalization

JB Nielsen, RL Hanson, HM Almughamsi… - Analytical …, 2019 - ACS Publications
Microfluidics is a growing field of study because these devices offer novel and versatile
approaches for addressing a range of scientific problems. Microfluidics have been used in …

Advances in point-of-care nucleic acid extraction technologies for rapid diagnosis of human and plant diseases

R Paul, E Ostermann, Q Wei - Biosensors and bioelectronics, 2020 - Elsevier
Global health and food security constantly face the challenge of emerging human and plant
diseases caused by bacteria, viruses, fungi, and other pathogens. Disease outbreaks such …

Advanced “lab-on-a-chip” to detect viruses–Current challenges and future perspectives

J Zhuang, J Yin, S Lv, B Wang, Y Mu - Biosensors and Bioelectronics, 2020 - Elsevier
Massive viral outbreaks draw attention to viruses that have not been thoroughly studied or
understood. In recent decades, microfluidic chips, known as “lab-on-a-chip”, appears as a …

A critical review of point-of-care diagnostic technologies to combat viral pandemics

ML Everitt, A Tillery, MG David, N Singh, A Borison… - Analytica Chimica …, 2021 - Elsevier
The COVID-19 global pandemic of 2019–2020 pointedly revealed the lack of diagnostic
solutions that are able to keep pace with the rapid spread of the virus. Despite the promise of …

The point-of-care-testing of nucleic acids by chip, cartridge and paper sensors

Y Xu, T Wang, Z Chen, L Jin, Z Wu, J Yan, X Zhao… - Chinese Chemical …, 2021 - Elsevier
Point-of-care nucleic acid testing (POCNAT) has played an important role in the outbreak of
infectious diseases (eg, COVID-19) over recent years. POCNAT aims to realize the rapid …

An overview on microfluidic systems for nucleic acids extraction from human raw samples

D Obino, M Vassalli, A Franceschi, A Alessandrini… - Sensors, 2021 - mdpi.com
Nucleic acid (NA) extraction is a basic step for genetic analysis, from scientific research to
diagnostic and forensic applications. It aims at preparing samples for its application with …

Dipstick-based rapid nucleic acids purification and CRISPR/Cas12a-mediated isothermal amplification for visual detection of African swine fever virus

S Qian, Y Chen, C Peng, X Wang, H Wu, Y Che… - Talanta, 2022 - Elsevier
African swine fever virus (ASFV) can cause highly contagious and fatal disease among
domestic pigs, resulting in considerable economic losses for swine breeders. There is a …

Advances in Simple, Rapid, and Contamination-Free Instantaneous Nucleic Acid Devices for Pathogen Detection

Y Wang, C Wang, Z Zhou, J Si, S Li, Y Zeng, Y Deng… - Biosensors, 2023 - mdpi.com
Pathogenic pathogens invade the human body through various pathways, causing damage
to host cells, tissues, and their functions, ultimately leading to the development of diseases …

Chemical trends in sample preparation for nucleic acid amplification testing (NAAT): a Review

SM Lee, HK Balakrishnan, EH Doeven, D Yuan… - Biosensors, 2023 - mdpi.com
Nucleic acid amplification testing facilitates the detection of disease through specific
genomic sequences and is attractive for point-of-need testing (PONT); in particular, the early …

UV-Assisted hyperbranched poly (β-amino ester) modification of a silica membrane for two-step microfluidic DNA extraction from blood

A Jagannath, Y Li, H Cong, J Hassan… - … Applied Materials & …, 2023 - ACS Publications
Integrating nucleic acid extraction in amplification-based point-of-care diagnostics will be a
significant feature for next-generation point-of-care virus detection devices. However …