[HTML][HTML] Lipo-nutritional quality of pork: The lipid composition, regulation, and molecular mechanisms of fatty acid deposition

W Yi, Q Huang, Y Wang, T Shan - Animal Nutrition, 2023 - Elsevier
Pork is one of the main meats consumed by people, and its nutritional value is closely
related to human health. The lipid deposition and composition of pork not only affect the …

The global perspective on peroxisome proliferator-activated receptor γ (PPARγ) in ectopic fat deposition: A review

Y Qiu, M Gan, X Wang, T Liao, Q Chen, Y Lei… - International journal of …, 2023 - Elsevier
Excessive expansion of adipocytes can have unhealthy consequences as excess free fatty
acids enter other tissues and cause ectopic fat deposition by resynthesizing triglycerides …

CRISPR/dCas9 tools: Epigenetic mechanism and application in gene transcriptional regulation

R Cai, R Lv, X Shi, G Yang, J Jin - International Journal of Molecular …, 2023 - mdpi.com
CRISPR/Cas9-mediated cleavage of DNA, which depends on the endonuclease activity of
Cas9, has been widely used for gene editing due to its excellent programmability and …

Alternative fat: redefining adipocytes for biomanufacturing cultivated meat

S Sugii, CYQ Wong, AKO Lwin, LJM Chew - Trends in Biotechnology, 2023 - cell.com
Cellular agriculture provides a potentially sustainable way of producing cultivated meat as
an alternative protein source. In addition to muscle and connective tissue, fat is an important …

One-step base editing in multiple genes by direct embryo injection for pig trait improvement

R Song, Y Wang, Q Zheng, J Yao, C Cao… - Science China Life …, 2022 - Springer
The precise and simultaneous acquisition of multiple beneficial alleles in the genome is in
great demand for the development of elite pig breeders. Cytidine base editors (CBEs) that …

Integration of ATAC-seq and RNA-seq analysis identifies key genes affecting intramuscular fat content in pigs

Z Xu, J Wu, J Zhou, Y Zhang, M Qiao, H Sun, Z Li… - Frontiers in …, 2022 - frontiersin.org
Meat quality is one of the most important economic traits in pig breeding and production, and
intramuscular fat (IMF) content is the major factor in improving meat quality. The IMF …

Different levels of autophagy induced by transient serum starvation regulate metabolism and differentiation of porcine skeletal muscle satellite cells

Y Wang, J Gao, B Fan, Y Hu, Y Yang, Y Wu, F Li… - Scientific Reports, 2023 - nature.com
This study aimed to investigate the effects of different levels of autophagy induced by
transient serum starvation on the metabolism, lipid metabolism, and differentiation of porcine …

Perspectives on scaling production of adipose tissue for food applications

JSK Yuen Jr, AJ Stout, NS Kawecki, SM Letcher… - Biomaterials, 2022 - Elsevier
With rising global demand for food proteins and significant environmental impact associated
with conventional animal agriculture, it is important to develop sustainable alternatives to …

CircADAMTS16 inhibits differentiation and promotes proliferation of bovine adipocytes by targeting miR-10167-3p

C Hu, X Feng, Y Ma, D Wei, L Zhang, S Wang, Y Ma - Cells, 2023 - mdpi.com
Circular RNAs (CircRNAs) are covalently closed-loop non-coding RNA (ncRNA) molecules
present in eukaryotes. Numerous studies have demonstrated that circRNAs are important …

Intermuscular adipose tissue in obesity and related disorders: cellular origins, biological characteristics and regulatory mechanisms

T Zhang, J Li, X Li, Y Liu - Frontiers in Endocrinology, 2023 - frontiersin.org
Intermuscular adipose tissue (IMAT) is a unique adipose depot interspersed between
muscle fibers (myofibers) or muscle groups. Numerous studies have shown that IMAT is …