Upon oxidative stress, mammalian cells rapidly reprogram their translation. This is
accompanied by the formation of stress granules (SGs), cytoplasmic ribonucleoprotein …

Accurately modeling the structures of proteins and their complexes using artificial
intelligence is revolutionizing molecular biology. Experimental data enable a candidate …

Living systems integrate biochemical reactions that determine the functional state of each
cell. Reactions are primarily mediated by proteins. In proteomic studies, these have been …

Comprehensive cancer genome studies have revealed genetically-defined subtypes of
prostate cancer with distinct truncal driver mutations. Because prostate cancer has been …

DifferentialNet is a novel database that provides users with differential interactome analysis
of human tissues (http://netbio. bgu. ac. il/diffnet/). Users query DifferentialNet by protein, and …

Research into the basic biology of human health and disease, as well as translational
human research and clinical applications, all benefit from the growing accessibility and …

Ortholog protein complexes are responsible for equivalent functions in different organisms.
However, during evolution, each organism adapts to meet its physiological needs and the …

The blossoming field of epitranscriptomics has recently garnered attention across many
fields by findings that chemical modifications on RNA have immense biological …

Complementary assays are required to comprehensively map complex biological entities
such as genomes, proteomes and interactome networks. However, how various assays can …

An increasing number of commonly prescribed drugs are known to interfere with
mitochondrial function, which is associated with almost half of all Food and Drug …