Etoposide is a podophyllotoxin derivative which delays progression of the cell cycle through
the late S or early G 2 phase. In vitro antitumour activity is dose and administration schedule …

PURPOSE The trial was undertaken to determine (1) the relative efficacy/toxicity of two
commonly used combination chemotherapy regimens in patients with extensive small-cell …

Abstracts Etoposide has demonstrated highly significant clinical activity against a wide
variety of neoplasms, including germ-cell malignancies, small-cell lung cancer, non …

PURPOSE A phase II trial in patients with limited-stage small-cell lung cancer treated with
induction etoposide/cisplatin plus twice-daily chest radiotherapy was conducted in an …

To determine if chemotherapy dose intensity (DI) influences treatment outcome, 60
published studies in limited-and extensive-stage small-cell carcinoma of the lung (SCCL) …

The role of chemotherapy in the management of patients with cancer of the paranasal sinus
has not been defined. An analysis of 24 evaluable patients treated with chemotherapy as …

The regimen of cisplatin, vincristine, doxorubicin, and etoposide (CODE) was designed to
double the dose intensity of these drugs in comparison with a standard regimen (alternating …

A retrospective study was conducted between two groups of dogs with histopathologically
diagnosed multicentric malignant lymphoma to determine if treatment with either short‐term …

Background: Many more phase II studies have favorable outcomes than the subsequent
phase III trials. We used historical data from phase II and phase III studies for patients with …

Abstract Background and Methods. Fifty‐one patients with small cell lung cancer (SCLC)
were treated with alternating urokinase (UK)‐cyclophosphamide‐doxorubicin (Adriamycin …