[HTML][HTML] SARS-CoV-2 mutations and their impact on diagnostics, therapeutics and vaccines

S Thakur, S Sasi, SG Pillai, A Nag, D Shukla… - Frontiers in …, 2022 - frontiersin.org
With the high rate of COVID-19 infections worldwide, the emergence of SARS-CoV-2
variants was inevitable. Several mutations have been identified in the SARS-CoV-2 …

A global picture: therapeutic perspectives for COVID-19

VP Chavda, C Kapadia, S Soni, R Prajapati… - …, 2022 - Future Medicine
The COVID-19 pandemic is a lethal virus outbreak by severe acute respiratory syndrome
coronavirus-2 (SARS-CoV-2), which has severely affected human lives and the global …

Temperature-responsive multilayer films based on block copolymer-coated silica nanoparticles for long-term release of favipiravir

L Xu, X Zhang, Z Chu, H Wang, Y Li… - ACS Applied Nano …, 2021 - ACS Publications
Using surface-initiated atom-transfer radical polymerization, temperature-responsive block
polymers were functionalized on the surface of silica nanocapsules (SNCs) by a “grafting …

[HTML][HTML] Structural basis for the in vitro efficacy of nirmatrelvir against SARS-CoV-2 variants

SE Greasley, S Noell, O Plotnikova, RA Ferre… - Journal of Biological …, 2022 - ASBMB
The COVID-19 pandemic continues to be a public health threat with emerging variants of
SARS-CoV-2. Nirmatrelvir (PF-07321332) is a reversible, covalent inhibitor targeting the …

[HTML][HTML] The impact of age difference on the efficacy and safety of COVID-19 vaccines: a systematic review and meta-analysis

J Wang, Y Tong, D Li, J Li, Y Li - Frontiers in immunology, 2021 - frontiersin.org
Objective This meta-analysis compared the efficacy and safety of five kinds of COVID-19
vaccines in different age groups (young adults and older adults), aiming to analyze the …

[HTML][HTML] Advances in the development of therapeutic strategies against COVID-19 and perspectives in the drug design for emerging SARS-CoV-2 variants

J Yin, C Li, C Ye, Z Ruan, Y Liang, Y Li, J Wu… - Computational and …, 2022 - Elsevier
Abstract Since Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) was
identified in late 2019, the coronavirus disease 2019 (COVID-19) pandemic has challenged …

Research on sleep status, body mass index, anxiety and depression of college students during the post-pandemic era in Wuhan, China

H Duan, M Gong, Q Zhang, X Huang, B Wan - Journal of Affective Disorders, 2022 - Elsevier
Objective Wuhan was the first Chinese city to be lockdown for the coronavirus disease 2019
(COVID-19) outbreak in springtime of 2020. The purpose of this study was to investigate the …

[PDF][PDF] Multi-omics blood atlas reveals unique features of immune and platelet responses to SARS-CoV-2 Omicron breakthrough infection

H Wang, C Liu, X Xie, M Niu, Y Wang, X Cheng… - Immunity, 2023 - cell.com
Although host responses to the ancestral SARS-CoV-2 strain are well described, those to
the new Omicron variants are less resolved. We profiled the clinical phenomes …

[HTML][HTML] Post-acute COVID-19 syndrome and kidney diseases: what do we know?

S Copur, M Berkkan, C Basile, K Tuttle, M Kanbay - Journal of nephrology, 2022 - Springer
COVID-19, a disease caused by a novel coronavirus (SARS-CoV-2), is a major global threat
that has turned into a pandemic. Despite the emergence of multiple vaccination alternatives …

[HTML][HTML] Coronavirus infection and cholesterol metabolism

J Dai, H Wang, Y Liao, L Tan, Y Sun, C Song… - Frontiers in …, 2022 - frontiersin.org
Host cholesterol metabolism remodeling is significantly associated with the spread of human
pathogenic coronaviruses, suggesting virus-host relationships could be affected by …