A comprehensive review about the molecular structure of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Insights into natural products against …

EM Saied, YA El-Maradny, AA Osman, AMG Darwish… - Pharmaceutics, 2021 - mdpi.com
In 2019, the world suffered from the emergence of COVID-19 infection, one of the most
difficult pandemics in recent history. Millions of confirmed deaths from this pandemic have …

Coronavirus infection and cholesterol metabolism

J Dai, H Wang, Y Liao, L Tan, Y Sun, C Song… - Frontiers in …, 2022 - frontiersin.org
Host cholesterol metabolism remodeling is significantly associated with the spread of human
pathogenic coronaviruses, suggesting virus-host relationships could be affected by …

Multi-omics blood atlas reveals unique features of immune and platelet responses to SARS-CoV-2 Omicron breakthrough infection

H Wang, C Liu, X Xie, M Niu, Y Wang, X Cheng… - Immunity, 2023 - cell.com
Although host responses to the ancestral SARS-CoV-2 strain are well described, those to
the new Omicron variants are less resolved. We profiled the clinical phenomes …

Associations between Serum Interleukins (IL‐1β, IL‐2, IL‐4, IL‐6, IL‐8, and IL‐10) and Disease Severity of COVID‐19: A Systematic Review and Meta‐Analysis

Y Chang, M Bai, Q You - BioMed Research International, 2022 - Wiley Online Library
Background. To investigate the association between interleukins (IL‐1β, IL‐2, IL‐4, IL‐6, IL‐
8, and IL‐10) and the disease severity of coronavirus disease 2019 (COVID‐19). Materials …

Safety and efficacy study of allogeneic human menstrual blood stromal cells secretome to treat severe COVID-19 patients: clinical trial phase I & II

M Fathi-Kazerooni, S Fattah-Ghazi, M Darzi… - Stem Cell Research & …, 2022 - Springer
Abstract Background Cell-free Mesenchymal stromal cells (MSCs) have been considered
due to their capacity to modulate the immune system and suppress cytokine storms caused …

PWM2Vec: An efficient embedding approach for viral host specification from coronavirus spike sequences

S Ali, B Bello, P Chourasia, RT Punathil, Y Zhou… - Biology, 2022 - mdpi.com
Simple Summary The family of coronaviruses comprises a diverse set of strains and variants
which cause diseases from the common cold to COVID-19. Moreover, they infect a wide …

Fc-engineered therapeutic antibodies: recent advances and future directions

DT Abdeldaim, K Schindowski - Pharmaceutics, 2023 - mdpi.com
Monoclonal therapeutic antibodies have revolutionized the treatment of cancer and other
diseases. Fc engineering aims to enhance the effector functions or half-life of therapeutic …

Drugs for COVID-19: An update

J Ceramella, D Iacopetta, MS Sinicropi, I Andreu… - Molecules, 2022 - mdpi.com
The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) was the seventh
known human coronavirus, and it was identified in Wuhan, Hubei province, China, in 2020. It …

After the hurricane: Anti-COVID-19 drugs development, molecular mechanisms of action and future perspectives

HO Khalifa, YM Al Ramahi - International Journal of Molecular Sciences, 2024 - mdpi.com
Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) is a new coronavirus in
the Coronaviridae family. The COVID-19 pandemic, caused by SARS-CoV-2, has …

The change of myopic prevalence in children and adolescents before and after COVID-19 pandemic in Suqian, China

H Chen, Y Liao, W Zhou, L Dong, W Wang, X Wang - PLoS One, 2022 - journals.plos.org
Purpose The aim of this study was to investigate the change of myopic prevalence in
students with different demographic characteristics before and after the COVID-19 pandemic …