With new data about different aspects of schizophrenia being continually generated, it
becomes necessary to periodically revisit exactly what we know. Along with a need to review …

Cortical morphology is a key determinant of cognitive ability and mental health. Its
development is a highly intricate process spanning decades, involving the coordinated …

Psychiatric genetics has made substantial progress in the last decade, providing new
insights into the genetic etiology of psychiatric disorders, and paving the way for precision …

Personality and cognitive function are heritable mental traits whose genetic foundations may
be distributed across interconnected brain functions. Previous studies have typically treated …

Patients with schizophrenia have consistently shown brain volumetric abnormalities,
implicating both etiological and pathological processes. However, the genetic relationship …

Abstract The breast cancer 1 (Brca1) susceptibility gene regulates the repair of reactive
oxygen species (ROS)-mediated DNA damage, which is implicated in neurodevelopmental …

Background Schizophrenia is a highly heritable brain disorder with a typical symptom onset
in early adulthood. The 2-hit hypothesis posits that schizophrenia results from differential …

Abstract Treatment resistant schizophrenia (TRS) is characterized by repeated treatment
failure with antipsychotics. A recent genome-wide association study (GWAS) of TRS showed …

BackgroundIndividuals with a first episode of psychosis (FEP) show rapid weight gain during
the first months of treatment, which is associated with a reduction in general physical health …

Background Schizophrenia (SCZ) and bipolar disorder (BD) are severe psychiatric
conditions that can involve symptoms of psychosis and cognitive dysfunction. The 2 …