Human skeletal muscle demonstrates remarkable plasticity, adapting to numerous external
stimuli including the habitual level of contractile loading. Accordingly, muscle function and …

Patients with heart failure (HF) usually present with skeletal muscle diseases of varying
severity, ranging from early fatigue on exercise to sarcopenia, sarcopenic obesity or …

Previous studies show that COVID-19 survivors have elevated muscle sympathetic nerve
activity (MSNA), endothelial dysfunction, and aortic stiffening. However, the neurovascular …

Mechanical distortion of working skeletal muscle induces sympathoexcitation via thin fibre
afferents, a reflex response known as the skeletal muscle mechanoreflex. However, to date …

Chronic obstructive pulmonary disease (COPD) is a constant and chronic narrowing of the
respiratory airways, with numerous associated symptoms, not always related to the …

The sympathetic nervous system is important for cardiovascular regulation, particularly
during acute stress. Efferent sympathetic outflow can be regulated in an organ-dependent …

Autonomic adjustments of the cardiovascular system are critical for initiating and sustaining
exercise by facilitating the redistribution of blood flow and oxygen delivery to meet the …

Chronic kidney disease (CKD) is characterized by pronounced exercise intolerance and
exaggerated blood pressure reactivity during exercise. Classic mechanisms of exercise …

• The exercise pressor reflex is involved in mediating the altered cardiovascular response to
exercise in T1D and its expression seems to change with disease duration, where an …

Peripheral artery diseases (PAD) increases muscle afferent nerve‐activated reflex
sympathetic nervous and blood pressure responses during exercise (termed as exercise …