EW Ely, AV Ramanan, CE Kartman… - The Lancet …, 2022 - thelancet.com
Summary Background The oral, selective Janus kinase 1/2 inhibitor baricitinib has shown efficacy in studies of hospitalised adults with COVID-19. COV-BARRIER (NCT04421027) …
J Declercq, E De Leeuw, BN Lambrecht - Cytokine, 2022 - Elsevier
Despite global vaccination programs, infections with severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) continue to cause severe disease with significant morbidity …
Ensuring high vaccination and even booster vaccination coverage is critical in preventing severe Coronavirus Disease 2019 (COVID-19). Among the various COVID-19 vaccines …
D Brokatzky, S Mostowy - Disease Models & Mechanisms, 2022 - journals.biologists.com
Pyroptosis, a regulated form of pro-inflammatory cell death, is characterised by cell lysis and by the release of cytokines, damage-and pathogen-associated molecular patterns. It plays …
V Trimarco, R Izzo, D Pacella, U Trama, MV Manzi… - BMC medicine, 2024 - Springer
Background While the augmented incidence of diabetes after COVID-19 has been widely confirmed, controversial results are available on the risk of developing hypertension during …
MJ Castleman, MM Stumpf, NR Therrien… - Journal of Experimental …, 2022 - rupress.org
Severe SARS-CoV-2 infection is associated with strong inflammation and autoantibody production against diverse self-antigens, suggesting a system-wide defect in B cell …
EA Starikova, AA Rubinstein, JT Mammedova… - Current Issues in …, 2023 - mdpi.com
More than a century has passed since arginine was discovered, but the metabolism of the amino acid never ceases to amaze researchers. Being a conditionally essential amino acid …
SA Khan, TKW Lee - Frontiers in microbiology, 2022 - frontiersin.org
COVID-19 disease is caused by SARS-CoV-2. Hyper-inflammation mediated by proinflammatory cytokines is humans' primary etiology of SARS-CoV-2 infection. Kochiae …
A Singh, R Ghosh, P Guchhait - Cytokine, 2023 - Elsevier
The endoplasmic reticulum (ER) is crucial for maintaining cellular homeostasis, and synthesis and folding of proteins and lipids. The ER is sensitive to stresses including viral …