Classification of COVID-19 patients into clinically relevant subsets by a novel machine learning pipeline using transcriptomic features
AR Daamen, P Bachali, AC Grammer… - International Journal of …, 2023 - mdpi.com
The persistent impact of the COVID-19 pandemic and heterogeneity in disease
manifestations point to a need for innovative approaches to identify drivers of immune …
manifestations point to a need for innovative approaches to identify drivers of immune …
Donor white blood cell differential is the single largest determinant of whole blood gene expression patterns
GC O'Connell, J Wang, C Smothers - Genomics, 2023 - Elsevier
It has become widely accepted that sample cellular composition is a significant determinant
of the gene expression patterns observed in any transcriptomic experiment performed with …
of the gene expression patterns observed in any transcriptomic experiment performed with …
Systems biology in asthma
The application of mathematical and computational analysis, together with the modelling of
biological and physiological processes, is transforming our understanding of the …
biological and physiological processes, is transforming our understanding of the …
Immune Correlates of Hyperglycemia and Vaccination in a Non-human Primate Model of Long-COVID
CS Palmer, C Perdios, M Abdel-Mohsen, J Mudd… - bioRxiv, 2023 - biorxiv.org
Hyperglycemia, and exacerbation of pre-existing deficits in glucose metabolism, are major
manifestations of the post-acute sequelae of SARS-CoV-2 (PASC). Our understanding of …
manifestations of the post-acute sequelae of SARS-CoV-2 (PASC). Our understanding of …
Precision medicine for pandemics: stratification of COVID-19 molecular phenotypes defined by topological analysis of global blood gene expression.
Precision medicine offers a promising avenue for better therapeutic responses to pandemics
such as COVID-19. This study leverages independent patient cohorts in Florence and Liège …
such as COVID-19. This study leverages independent patient cohorts in Florence and Liège …
Persistent Homology Identifies Pathways Associated with Hepatocellular Carcinoma from Peripheral Blood Samples
Topological data analysis (TDA) methods have recently emerged as powerful tools for
uncovering intricate patterns and relationships in complex biological data, demonstrating …
uncovering intricate patterns and relationships in complex biological data, demonstrating …
Differentiation of COVID-19 from other emergency infectious disease presentations using whole blood transcriptomics then rapid qPCR: a case-control and …
HK Li, HR Jackson, L Miglietta, D Habgood-Coote… - medRxiv, 2023 - medrxiv.org
Background. The overlapping clinical presentations of patients with acute respiratory
disease can complicate disease diagnosis. Whilst PCR diagnostic methods to identify SARS …
disease can complicate disease diagnosis. Whilst PCR diagnostic methods to identify SARS …
Systems Biology in Asthma
R Djukanović, F Chung… - Precision Approaches to …, 2023 - books.google.com
The application of mathematical and computational analysis, together with the modelling of
biological and physiological processes, is transforming our understanding of the …
biological and physiological processes, is transforming our understanding of the …